330785-78-9

Basic information

• Product Name: 1-Propanone, 1-[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymeth yl)-1-pyrrolidinyl]-5-pyrimidinyl]-3-(4-morpholinyl)-
• CAS NO: 330785-78-9
• Molecular Formula: C24H32ClN5O4
• Molecular Weight: 490.002
• Mol File: 330785-78-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymeth yl)-1-pyrrolidinyl]-5-pyrimidinyl]-3-(4-morpholinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymeth yl)-1-pyrrolidinyl]-5-pyrimidinyl]-3-(4-morpholinyl)-(330785-78-9)
• EPA Substance Registry System: 1-Propanone, 1-[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymeth yl)-1-pyrrolidinyl]-5-pyrimidinyl]-3-(4-morpholinyl)-(330785-78-9)

Safety Data

• Hazardous Substances Data: 330785-78-9(Hazardous Substances Data)

Upstream product

• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 115514-77-7 (3-chloro-4-methoxyphenyl)methanamine 
• 330785-87-0 4-(3-Chloro-4-methoxy-benzylamino)-2-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-pyrimidine-5-carbaldehyde 
• 330786-34-0 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylic acid 
• 330785-86-9 4-(3-Chloro-4-methoxy-benzylamino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde 
• 330785-81-4 ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate 
• 110-91-8 morpholine 
• 330785-94-9 1-[4-(3-Chloro-4-methoxy-benzylamino)-2-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-pyrimidin-5-yl]-propenon 

Relevant articles and documents

8-(3-Chloro-4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one derivatives as potent and selective phosphodiesterase 5 inhibitors

A novel series of highly selective phosphodiesterase 5 (PDE5) inhibitors was found. 8H-Pyrido[2,3-d]pyrimidin-7-one derivatives bearing an (S)-2-(hydroxymethyl)pyrrolidin-1-yl group at the 2-position and a 3-chloro-4-methoxybenzyl group at the 8-position

PYRIDOPYRIMIDINE OR NAPHTHYRIDINE DERIVATIVE

A pyridopyrimidine or a naphthyridine derivative of the formula (I): wherein R1 is an optionally substituted nitrogen-containing heterocyclic group, etc.; R2 is H or a lower alkyl group; R3 is H or an optionally substitute