330785-86-9

Basic information

• Product Name: 5-Pyrimidinecarboxaldehyde, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-
• CAS NO: 330785-86-9
• Molecular Formula: C14H14ClN3O2S
• Molecular Weight: 323.803
• Mol File: 330785-86-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxaldehyde, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxaldehyde, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-(330785-86-9)
• EPA Substance Registry System: 5-Pyrimidinecarboxaldehyde, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-(330785-86-9)

Safety Data

• Hazardous Substances Data: 330785-86-9(Hazardous Substances Data)

Upstream product

• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 115514-77-7 (3-chloro-4-methoxyphenyl)methanamine 
• 330786-34-0 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylic acid 
• 330785-81-4 ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate 
• 330785-85-8 [4-(3-Chloro-4-methoxy-benzylamino)-2-methylsulfanyl-pyrimidin-5-yl]-methanol 
• 108-20-3 di-isopropyl ether 

Downstream Products

• 454486-76-1 8-(3-Chloro-4-methoxy-benzyl)-2-methylsulfanyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid methyl ester 
• 454486-92-1 [4-(3-Chloro-4-methoxy-benzylamino)-2-methylsulfanyl-pyrimidin-5-yl]-(1-methyl-1H-imidazol-2-yl)-methanol 
• 372114-66-4 [4-(3-Chloro-4-methoxy-benzyl)-2-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-pyrimidin-5-yl]-pyridin-2-yl-methanone 
• 330785-94-9 1-[4-(3-Chloro-4-methoxy-benzylamino)-2-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-pyrimidin-5-yl]-propenon 
• 372113-71-8 (S)-4-(3-chloro-4-methoxybenzylamino)-2-(2-hydroxymethyl-1-pyrrolidinyl)5-(1-methyl-2-imidazolylcarbonyl)pyrimidine 
• 330785-78-9 1-[4-(3-Chloro-4-methoxy-benzylamino)-2-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-pyrimidin-5-yl]-3-morpholin-4-yl-propan-1-one 
• 454486-81-8 8-(3-Chloro-4-methoxy-benzyl)-5-methyl-2-methylsulfanyl-5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one 
• 372113-70-7 [4-(3-Chloro-4-methoxy-benzylamino)-2-methylsulfanyl-pyrimidin-5-yl]-(1-methyl-1H-imidazol-2-yl)-methanone 
• 330785-87-0 4-(3-Chloro-4-methoxy-benzylamino)-2-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-pyrimidine-5-carbaldehyde 
• 454486-73-8 C₁₇H₁₈ClN₃O₃S 

Relevant articles and documents

8-(3-Chloro-4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one derivatives as potent and selective phosphodiesterase 5 inhibitors

A novel series of highly selective phosphodiesterase 5 (PDE5) inhibitors was found. 8H-Pyrido[2,3-d]pyrimidin-7-one derivatives bearing an (S)-2-(hydroxymethyl)pyrrolidin-1-yl group at the 2-position and a 3-chloro-4-methoxybenzyl group at the 8-position

PYRIDOPYRIMIDINE OR NAPHTHYRIDINE DERIVATIVE

A pyridopyrimidine or a naphthyridine derivative of the formula (I): wherein R1 is an optionally substituted nitrogen-containing heterocyclic group, etc.; R2 is H or a lower alkyl group; R3 is H or an optionally substitute