330801-35-9Relevant academic research and scientific papers
Synthesis of (Z)-fluoroalkene dipeptide isosteres utilizing organocopper-mediated reduction of γ,γ-difluoro-α,β-enoates
Otaka, Akira,Watanabe, Hideaki,Mitsuyama, Etsuko,Yukimasa, Akira,Tamamura, Hirokazu,Fujii, Nobutaka
, p. 285 - 287 (2007/10/03)
γ,γ-Difluoro-α,β-enoates are reduced with organocopper reagents to afford the corresponding γ-fluoro-β,γ-enoates. This organocopper-mediated reduction was applied to the synthesis of (Z)-fluoroalkene dipeptide isosteres.
