33082-03-0Relevant articles and documents
3-Cyano-5-thiazaheteroaryl-dihydropyridine and the use thereof for the treatment of cardiovascular diseases
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Page/Page column 17, (2010/10/03)
The present application relates to novel aryl-substituted 3-cyano-5-thiazolyl- and 3-cyano-5-thiadiazolyl-1,4-dihydropyridines, a process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.
SYNTHETIC APPLICATIONS OF 2-CHLOROOXIRANES: PREPARATION OF THIAZOLES, DIHYDROTHIAZOLES AND SELENAZOLES
Gasteiger, Johann,Herzig, Christian
, p. 2607 - 2611 (2007/10/02)
The reaction of 2-chlorooxiranes 1 with thioamides and thioureas provides access to thiazoles, 4-hydroxy-4,5-dihydrothiazoles and 2-imino-2,3-dihydrothiazoles under mild conditions and excellent yields.With 1 and selenourea, near quantitative yields of se