330861-68-2

Upstream product

• 3300-51-4 p-Trifluoromethylbenzylamine 
• 24550-58-1 5-cyanomethyl-2-methoxybenzoic acid 
• 7252-24-6 3-carbomethoxy-4-methoxybenzyl chloride 
• 78515-16-9 methyl 5-formyl-2-methoxybenzoate 
• 191604-81-6 methyl 5-(hydroxymethyl)-2-methoxybenzoate 
• 24550-59-2 5-cyanomethyl-2-methoxy-benzoic acid methyl ester 
• 2942-58-7 diethyl cyanophosphonate 

Downstream Products

• 330861-69-3 5-carbamoylmethyl-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide 

Relevant academic research and scientific papers

Design, synthesis and evaluation of substituted phenylpropanoic acid derivatives as peroxisome proliferator-activated receptor (PPAR) activators: Novel human PPARα-selective activators

A series of substituted phenylpropanoic acid derivatives was prepared as part of a search for subtype-selective human peroxisome proliferator-activated receptor (PPAR) activators. Structure-activity relationship studies indicated that the substituent at the α-position of the carboxyl group plays a key role in determining the potency and the selectivity for PPAR transactivation.

O-ANISAMIDE DERIVATIVES

The invention provides o-anisamide derivatives and their addition salts effective for the prevention and/or therapy of metabolic diseases such as hyperlipidemia and diabetes, in which peroxisome proliferator-activated receptor (PPAR) being intranuclear re