330944-15-5Relevant academic research and scientific papers
Synthesis and structure-affinity relationship investigations of 5-aminomethyl and 5-carbamoyl analogues of the antipsychotic sertindole. A new class of selective α1 adrenoceptor antagonists
Balle, Thomas,Perregaard, Jens,Larsen, Anna K.,Ramirez, Martha Teresa,Soby, Karina Krojer,Liljefors, Tommy,Andersen, Kim
, p. 1065 - 1078 (2007/10/03)
A new class of selective α1 adrenoceptor antagonists derived from the antipsychotic drug sertindole is described. The most potent and selective compound 1-(2-{4-[5-aminomethyl-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl} ethyl)-2-imidazolid
5-aminoalkyl and 5-aminocarbonyl substituted indoles
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, (2008/06/13)
The present invention relates to 5-aminoalkyl and 5-aminocarbonyl substituted indole derivatives having formula (1), wherein R1 is-(CH2)n-1-CONR10R11, -(CH2)n-CONR10R
