330945-07-8

Basic information

• Product Name: 2-benzyl 1-(tert-butyl) (2S,3S)-3-hydroxypyrrolidine-1,2-dicarboxylate
• Synonyms: 2-benzyl 1-(tert-butyl) (2S,3S)-3-hydroxypyrrolidine-1,2-dicarboxylate
• CAS NO: 330945-07-8
• Molecular Weight: 321.373
• Mol File: 330945-07-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-benzyl 1-(tert-butyl) (2S,3S)-3-hydroxypyrrolidine-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl 1-(tert-butyl) (2S,3S)-3-hydroxypyrrolidine-1,2-dicarboxylate(330945-07-8)
• EPA Substance Registry System: 2-benzyl 1-(tert-butyl) (2S,3S)-3-hydroxypyrrolidine-1,2-dicarboxylate(330945-07-8)

Safety Data

• Hazardous Substances Data: 330945-07-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 100-39-0 benzyl bromide 
• 4298-08-2 trans-3-hydroxy-L-proline 
• 187039-57-2 (2S,3S)-1-(tert-butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid 

Downstream Products

• 871981-52-1 ((3S)-acetoxy-1-tert-butoxycarbonyl-(2S)-pyrrolidinyl)carboxylic acid benzyl ester 
• 936703-36-5 C₅₇H₇₄N₆O₁₅ 
• 936703-32-1 C₂₄H₃₅N₃O₈ 
• 330945-11-4 2-benzyl 1-(tert-butyl) (2R,3R)-3-fluoropyrrolidine-1,2-dicarboxylate 
• 330945-21-6 2-benzyl 1-(tert-butyl) (2R,3S)-3-fluoropyrrolidine-1,2-dicarboxylate 
• 330945-23-8 (2R,3S)-1-tert-butoxycarbonyl-3-fluoro-pyrrolidine-2-carboxylic acid 
• 186132-95-6 2-benzyl 1-(tert-butyl)(2S,3R)-3-hydroxypyrrolidine-1,2-dicarboxylate 

Relevant articles and documents

Synthesis of optically pure N-Boc-protected (2R,3R)- and (2R,3S)-3-fluoroprolines

Non-protein amino acids (2R,3R)- and (2R,3S)-3-fluoroprolines were synthesized as novel probes for studying the cis/trans isomerization of the amino acyl-proline peptide bond. The N-Boc-protected target compounds were obtained as optically pure material s

THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF

The invention provides compounds having the general Formula (I); and pharmaceutically acceptable salts thereof; wherein the variables RA, RAA, subscript n, subscript q, ring A, X2, L, subscript m, X1, R1, R2, R3, R4, R5, D and E have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.