33100-30-0Relevant academic research and scientific papers
Analgesic and myotonolytic preparations
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, (2008/06/13)
Compositions having enhanced analgesic and myotonolytic activity comprising as active agents (a) an analeptically active quinazolinone and (b) a centrally acting myotonolytic.
Antiinflammatory Properties of 8-Aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones
Houlihan, William J.,Cooke, George,Bochoven, Richard Van,Perrine, John,Takesue, Edward I.,Jukniewicz, E.
, p. 1110 - 1113 (2007/10/02)
A series of 8-aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones was prepared and evaluated for antiinflammatory activity.The 8-phenyl-, 8-(3-fluorophenyl)-, and 8-(4-fluorophenyl)-2H-1,3-dioxoloquinazolin-6(5H)-ones and the 8-phenyl-2H-1,3-dioxoloquinazolin-6(5H)-thione were found to exhibit activity in the range of indomethacin and proquazone.
Preparation of quinazolin-2(1H)-ones
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, (2008/06/13)
The invention provides a process for the production of 4-phenyl-2(1H)-quinazolinones by cyclising a corresponding 2-aminobenzophenone with urea or an alkylcarbamate in the presence of an aromatic acid. The products are known anti-inflammatory agents.
