331-30-6

Basic information

• Product Name: N-(4-bromo-3-methylphenyl)acetamide
• Synonyms: N-(4-bromo-3-methylphenyl)acetamide;N-(4-fluoro-3-Methylphenyl)acetaMide
• CAS NO: 331-30-6
• Molecular Formula: C₉H₁₀FNO
• Molecular Weight: 228.0858
• Mol File: 331-30-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-bromo-3-methylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromo-3-methylphenyl)acetamide(331-30-6)
• EPA Substance Registry System: N-(4-bromo-3-methylphenyl)acetamide(331-30-6)

Safety Data

• Hazardous Substances Data: 331-30-6(Hazardous Substances Data)

Usage

General Description

N-(4-bromo-3-methylphenyl)acetamide is a chemical compound with the molecular formula C10H11BrNO. It is a derivative of acetamide, containing a 4-bromo-3-methylphenyl group attached to the nitrogen atom. N-(4-bromo-3-methylphenyl)acetamide is used in the synthesis of various pharmaceuticals and organic compounds. It has also been studied for its potential application in medicinal chemistry, particularly for its antimicrobial and analgesic properties. The presence of the bromine and methyl groups in the compound's structure can influence its stability and reactivity, making it an important target for further research and development in the field of organic chemistry and drug discovery.

Upstream product

• 403-00-9 1-(4-fluoro-3-methyl-phenyl)-ethanone oxime 
• 455-88-9 5-nitro-2-fluorotoluene 
• 452-69-7 3-methyl-4-fluoroaniline 
• 108-24-7 acetic anhydride 

Downstream Products

• 97398-89-5 N-acetyl-4-fluoro-5-methyl-2-nitrobenzenamine 
• 102568-75-2 N-ethyl-4-fluoro-3-methyl-aniline 
• 97389-11-2 4-fluoro-5-methyl-1,2-benzenediamine 
• 97389-10-1 4-fluoro-5-methyl-2-nitrobenzenamine 
• 97389-17-8 3,4,7-trimethyl-3H-imidazo<4,5-f>quinoxalin-2-amine 
• 95896-78-9 2-amino-3,4,8-trimethylimidazo-[4,5-f]quinoxaline 
• 97389-09-8 N-acetyl-4-fluoro-3-methyl-2-nitrobenzenamine 
• 452-69-7 3-methyl-4-fluoroaniline 

Relevant articles and documents

An Electrochemical Beckmann Rearrangement: Traditional Reaction via Modern Radical Mechanism

Abstract: Electrosynthesis as a potential means of introducing heteroatoms into the carbon framework is rarely studied. Herein, the electrochemical Beckmann rearrangement, i. e. the direct electrolysis of ketoximes to amides, is presented for the first time. Using a constant current as the driving force, the reaction can be easily carried out under neutral conditions at room temperature. Based on a series of mechanistic studies, a novel radical Beckmann rearrangement mechanism is proposed. This electrochemical Beckmann rearrangement does not follow the trans-migration rule of the classical Beckmann rearrangement.

HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

A convenient synthesis of the potent mutagen 3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine.

The highly mutagenic title compound (4,8-DiMeIQx) was synthesized in 13% overall yield from 2-fluoro-5-nitrotoluene in eight operations. The average operation yield was 83%. The reaction sequence used gave, in addition to the title compound, the isomer 3,4,7-trimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine (4,7-DiMeIQx).