33119-91-4

Upstream product

• 33119-82-3 4-cholorobenzaldehyde 2-(2-benzothiazolyl)hydrazone 
• 13037-60-0 1-bromo-2-isothiocyanatobenzene 
• 149-30-4 2-Mercaptobenzothiazole 
• 33119-97-0 4-chloro-benzoic acid N'-benzothiazol-2-yl-hydrazide 
• 615-21-4 1,3-benzothiazol-2-ylhydrazine 
• 122-01-0 4-chloro-benzoyl chloride 
• 104-88-1 4-chlorobenzaldehyde 
• 33119-86-7 N-acetyl-N-benzothiazol-2-yl-N'-(4-chloro-benzoyl)-hydrazine 
• 37120-62-0 N'-benzothiazol-2-yl-4-chloro-benzohydrazonoyl bromide 

Relevant academic research and scientific papers

Convenient synthesis of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles with 1 mol% CuCl2·2H2O as catalyst in water

A convenient and efficient procedure for the synthesis of benzo[4,5]thiazolo [2,3-c][1,2,4]triazoles has been developed via a tandem intermolecular C-N bond and intramolecular C-S bond formation sequence from o-bromo-arylisothiocyanates and aroylhydrazides. A series of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles were provided in excellent overall yields with 1 mol% CuCl2·2H2O/1 mol% 1,10-phenanthroline as the catalyst and water as the solvent. This journal is

Synthesis of new triazolo and pyrazolo benzothiazoles

Benzothiazole-2-thiol 1 on heating with excess of hydrazine hydrate yields 2-hydrazino-1,3-benzothiazole (2). Compound 2 on reaction with carbon disulfide in alkaline medium affords [1,2,4] triazolo [3,4-b] [1,3] benzothiazole-3-thiol (3). Condensation of 2 with various substituted aryl aldehydes yields corresponding hydrazine derivatives (4), which on cyclisation with acetic anhydride gave corresponding [1,2,4] triazolo [3,4-6] [1,3] benzothiazoles (5). Some other triazolo derivatives (6,7,8) of benzothiazole were obtained by the cyclization of 2 with benzoyl chloride, acetyl chloride and formic acid respectively. Again compound 2 on condensation with acetyl acetone and ethylacetoacetate gives pyrazolo derivatives (9,10) respectively. The synthesized compounds were characterized by elemental and spectral analysis.

Thallium(III) salts mediated oxidative cyclization of arenecarbaldehyde benzothiazol-2-ylhydrazones to bridged head nitrogen heterocycles

Oxidation of arenecarbaldehydebenzothiazol-2-ylhydrazones (4) with thallium (III) acetate in refluxing acetic acid, thallium (III) acetate and thallium (III) nitrate in acetonitrile in presence of p-toluene sulphonic acid afforded 3-aryl-1,2,4-triazolo [3