33130-90-4

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 31932-87-3 D-α-amino-m-hydroxyphenylacetic acid 
• 108594-41-8 (2S)-(+)-2-<(1S,2S)-(2-Hydroxy-1-hydroxymethyl-2-phenylethyl)amino>-2-(3-methoxyphenyl)essigsaeure 
• 108647-55-8 (2S)-(+)-2-(3-Methoxyphenyl)glycin 
• 41840-28-2 S-tert-butoxycarbonyl-4,6-dimethyl-2-mercaptopyrimidine 
• 71301-82-1 (S)-3-hydroxyphenylglycine 

Relevant academic research and scientific papers

Nonproteinogenic Amino Acids, IV. - EPC Synthesis of L-(+)-Forphenicine

Enantiomerically pure L-(+)-forphenicine (12) is synthesized starting from purchasable 3-methoxybenzaldehyde (1) by the use of (4S,5S)-(+)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane (2) as a chiral auxiliary and prussic acid. 12 is identical with the natural product which has been isolated from the culture broth of an Actinomyces species and which is known to be a potent inhibitor of alkaline phosphatase.

3-Propenyl cephalosporin derivatives

The present invention relates to 7-[(D)-2-amino-2-(3-hydroxyphenyl)acetamido]-3-[(Z)-1-propenyl]-3-cephem-4-carboxylic acid, which is an orally active antibiotic against Gram-positive and Gram-negative bacteria.