3314-44-1

Basic information

• Product Name: Phenol, 4-(4,5-dihydro-1-phenyl-1H-pyrazol-3-yl)-
• CAS NO: 3314-44-1
• Molecular Formula: C15H14N2O
• Molecular Weight: 238.289
• Mol File: 3314-44-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(4,5-dihydro-1-phenyl-1H-pyrazol-3-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(4,5-dihydro-1-phenyl-1H-pyrazol-3-yl)-(3314-44-1)
• EPA Substance Registry System: Phenol, 4-(4,5-dihydro-1-phenyl-1H-pyrazol-3-yl)-(3314-44-1)

Safety Data

• Hazardous Substances Data: 3314-44-1(Hazardous Substances Data)

Upstream product

• 2125-51-1 3-dimethylamino-1-(p-hydroxyphenyl)-1-propanone hydrochloride 
• 100-63-0 phenylhydrazine 
• 59-88-1 phenylhydrazine hydrochloride 

Relevant articles and documents

Utility of Ketonic Mannich Bases in Synthesis of Some New Functionalized 2-Pyrazolines

The styryl ketonic Mannich base 2 has been used as a precursor in the synthesis of 2-pyrazolines having a basic side chain at C-3 and a phenolic Mannich base at C-5. Treatment of the bis(styryl ketonic bases) 6a and 8a with phenylhydrazine affords the bis(3-functionalized 2-pyrazolines) 7 and 9. The transamination between the styryl keto base 10 and 4-aminoantipyrine leads to 12, which reacts with piperazine to give 13. N-Nitrosation of the sec-Mannich bases 15a–d followed by reductive cyclization affords 2-pyrazolines 17a–d. The keto base 14b has been used for the synthesis of 2-pyrazolines having a phenolic Mannich base at C-3 and its reaction with 3,5-dimethyl-1H-pyrazole affords 23. The alkylation of 3-methyl-1-phenyl-2-pyrazolin-5-one with the bis(Mannich base) 25 was investigated.