332057-37-1

Basic information

• Product Name: (2E)-2-(1,3-benzodioxol-5-ylmethylidene)-1-benzothiophen-3(2H)-one
• CAS NO: 332057-37-1
• Molecular Formula: C₁₆H₁₀O₃S
• Molecular Weight: 282.3138
• Mol File: 332057-37-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 469.3°C at 760 mmHg
• Flash Point: 243.1°C
• Density: 1.459g/cm³
• Vapor Pressure: 5.58E-09mmHg at 25°C
• Refractive Index: 1.751
• CAS DataBase Reference: (2E)-2-(1,3-benzodioxol-5-ylmethylidene)-1-benzothiophen-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-(1,3-benzodioxol-5-ylmethylidene)-1-benzothiophen-3(2H)-one(332057-37-1)
• EPA Substance Registry System: (2E)-2-(1,3-benzodioxol-5-ylmethylidene)-1-benzothiophen-3(2H)-one(332057-37-1)

Safety Data

• Hazardous Substances Data: 332057-37-1(Hazardous Substances Data)

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 120-57-0 piperonal 
• 1441-97-0 2'-(methylthio)acetophenone 

Relevant articles and documents

Iodine-catalyzed intramolecular oxidative thiolation of vinylic carbon-hydrogen bonds via tandem iodocyclization and dehydroiodination: Construction of 2-methylene-3-thiophenones

A metal-free vinylic carbon-hydrogen bond thiolation has been developed. Under the catalysis of iodine (10 mol%), the cyclization of α-alkenoyl ketene dithioacetals afforded a broad range of polyfunctionalized 2-methylene-3-thiophenones in good selectivity with moderate to excellent yields via tandem iodocyclization and dehydroiodination. The synthetic strategy can also be extended to the cyclization of ortho-methylthiophenyl vinyl ketones leading to 2-methylene-3-benzothiophenones.