332113-79-8Relevant academic research and scientific papers
NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF
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Paragraph 0069; 0107, (2021/11/04)
The present invention relates to novel hydrazone derivatives in which a terminal amine group is substituted with an aryl group or a heteroaryl group, and uses thereof.
SARS-COV-2 INHIBITORS HAVING COVALENT MODIFICATIONS FOR TREATING CORONAVIRUS INFECTIONS
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Paragraph 00267-00270, (2021/11/06)
Provided herein are compounds, pharmaceutical compositions and methods for treating a SARS-CoV-2 infection.
Novel hydrazone derivatives comprising aryl or heteroaryl group substituted at terminal amine and use thereof
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Paragraph 0325; 0327; 0328; 0507; 0509; 0510, (2020/08/28)
The present invention relates to novel hydrazone derivatives with an aryl or heteroaryl group substituted at a terminal amine group thereof and a use thereof.
Synthesis of 5-arylthiazoles. Comparative study between Suzuki cross-coupling reaction and direct arylation
Primas, Nicolas,Bouillon, Alexandre,Lancelot, Jean-Charles,El-Kashef, Hussein,Rault, Sylvain
experimental part, p. 5739 - 5746 (2009/12/03)
A facile synthetic route to the new thiazol-5-ylboronic acid pinacol ester was described herein. Its reactivity toward Suzuki cross-coupling reaction was studied to provide various 5-arylthiazoles. A comparative study between Suzuki cross-coupling reactio
Preparation of 2- and 5-aryl substituted thiazoles via palladium-catalyzed Negishi cross-coupling
Jensen,Skj?rb?k,Veds?
, p. 128 - 134 (2007/10/03)
2-Aryl substituted thiazoles 3a-k were prepared by oxidative insertion of zinc into 2-bromothiazole (1) followed by palladium(0)-catalyzed Negishi cross-coupling in a one-pot procedure. 5-Aryl substituted thiazoles 6a-i were prepared by regioselective C-5 lithiation of 2-(trimethylsilyl)thiazole (4) followed by transmetalation with zinc chloride and palladium(0)-catalyzed Negishi cross-coupling in a one-pot procedure. The synthetic sequences were combined to give 2,5-diaryl substituted thiazoles 8a,b and 10 via stepwise C-2 and C-5 arylation and vice versa.
