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(2-amino(3-pyridyl))-N-(4-chlorophenyl)carboxamide, also known as BCTC, is a potent and selective antagonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1). It is a chemical compound that has been shown to block the activation of TRPV1 by various agonists, including capsaicin and heat. TRPV1 is a non-selective cation channel that is expressed in nociceptive neurons and is involved in the sensation of pain. BCTC has demonstrated potential as a therapeutic agent for the treatment of pain and inflammatory conditions.

332419-46-2

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332419-46-2 Usage

Uses

Used in Pharmaceutical Industry:
(2-amino(3-pyridyl))-N-(4-chlorophenyl)carboxamide is used as a therapeutic agent for the treatment of pain and inflammatory conditions. It works by blocking the activation of TRPV1, a non-selective cation channel involved in the sensation of pain. This makes it a valuable tool in the study of pain perception and TRPV1 function, as well as a potential treatment for various pain and inflammatory conditions.
Used in Research Applications:
(2-amino(3-pyridyl))-N-(4-chlorophenyl)carboxamide is used as a research tool for studying the function and role of TRPV1 in pain perception. By blocking the activation of TRPV1, researchers can gain a better understanding of the mechanisms underlying pain and inflammation, and potentially identify new targets for the development of therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 332419-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,2,4,1 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 332419-46:
(8*3)+(7*3)+(6*2)+(5*4)+(4*1)+(3*9)+(2*4)+(1*6)=122
122 % 10 = 2
So 332419-46-2 is a valid CAS Registry Number.

332419-46-2Relevant academic research and scientific papers

Substituted alkylamine derivatives and methods of use

-

, (2008/06/13)

Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Studies on aroylation of 2,3-pyridinediamines

Dubey,Vinod Kumar

, p. 746 - 751 (2007/10/03)

The reaction of 2,3-pyridinediamine 1a and its 5-bromo analogue 1b, independently, with acid chloride or anhydride does not yield the diaroyl derivative and instead yields the cyclised product 3 or the monoaroyl derivative 4 depending upon the conditions.

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