952-13-6Relevant academic research and scientific papers
Regioselective C2-arylation of imidazo[4,5-b]pyridines
Macdonald, Jonathan,Oldfield, Victoria,Bavetsias, Vassilios,Blagg, Julian
supporting information, p. 2335 - 2347 (2013/04/23)
We show that N3-MEM-protected imidazo[4,5-b]pyridines undergo efficient C2-functionalisation via direct C-H arylation. Twenty-two substituted imidazo[4,5-b]pyridines are prepared and iterative, selective elaboration of functionalised imidazo[4,5-b]pyridin
Eco-friendly and facile synthesis of 2-substituted-1H-imidazo[4,5-b]pyridine in aqueous medium by air oxidation
Kale, Rajesh P.,Shaikh, Mohammad U.,Jadhav, Ganesh R.,Gill, Charansingh H.
scheme or table, p. 1780 - 1782 (2009/07/19)
We report a new environmentally-benign, convenient, and facile methodology for the synthesis of 2-substituted-1H-imidazo[4,5-b]pyridine. The reaction of 2,3-diaminopyridine with substituted aryl aldehydes in water under thermal conditions without the use
Unambiguous structural assignment of monoanils obtained from 2,3-pyridinediamines
Dubey,Kumar, R. Vinod,Kulkarni, Subhash M.,Sunder, G. Hema,Smith, Graham,Kennard, Collin H. L.
, p. 952 - 956 (2007/10/03)
The reaction of 2,3-pyridinediamine la and its 5-bromo analogue lb independently with aromatic aldehydes results in the formation of 2-amino-and 5-bromo-2-amino-3-arylideneaminopyridines (2a and 2b) respectively. The structure of 2 has been confirmed by single crystal X-ray analysis, thereby ruling out the alternate structure for these compounds.
Structure and reactions of monoanils obtained from 2,3-pyridinediamines
Dubey,Kulkarni,Vinod Kumar
, p. 361 - 367 (2007/10/03)
The reaction of 2,3-pyridinediamines 1 with aromatic aldehydes results in the formation of 2-amino-3-arylideneaminopyridines 2 respectively. Dehydrogenative cyclisation of 2 with different reagents give 2-aryl-1H-imidazo[4,5-b]pyridines 4. Reactions of 2 with different reagents have been described.
Studies on aroylation of 2,3-pyridinediamines
Dubey,Vinod Kumar
, p. 746 - 751 (2007/10/03)
The reaction of 2,3-pyridinediamine 1a and its 5-bromo analogue 1b, independently, with acid chloride or anhydride does not yield the diaroyl derivative and instead yields the cyclised product 3 or the monoaroyl derivative 4 depending upon the conditions.
Synthesis of Amidines and Attempted Synthesis of Imidazoazines by Reactions of Lithiated β-Aminoazines with Nitriles
Redhouse, Alan D.,Thompson, Robin J.,Wakefield, Basil J.,Wardell, Jacklyn A.
, p. 7619 - 7628 (2007/10/02)
Deprotonation of 3-aminopyridine, followed by reaction of aromatic nitriles, gives N-(3-pyridyl)-benzamidines, and other β-aminoazines (pyridines, quinolines, pyrazines, pyrimidines) react similarly.Attempts to cyclise the amidines to, for example, 2-aryl
Fused imidazoheterocyclic compounds and pharmaceutical compositions
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, (2008/06/13)
Imidazoheterocyclic compounds having the formula: STR1 wherein the A ring is pyridine in any of its four positions; B is carbonyl, thioxomethyl or hydroxymethylene; Z is hydrogen, halogen, loweralkyl, hydroxy, loweralkoxy, diloweralkylamino or nitro; Ar i
PREPARATION OF 2-ARYL-SUBSTITUTED IMIDAZOPYRIDINES AND IMIDAZOPYRIDINES
Yutilov, Yu. M.,Shcherbina, L. I.
, p. 529 - 535 (2007/10/02)
It is proposed that sulfur be used as the oxidizing agent in the synthesis of 2-arylimidazopyridines from o-diaminopyridines and aromatic (heteroaromatic) aldehydes.Benzyl alcohols and benzylpyridinium salts can be used in place of aldehydes. 2-Phenylimid
