33253-32-6

Basic information

• Product Name: 4-HYDROXY-6-PHENETHYL-PYRAN-2-ONE
• Synonyms: 4-HYDROXY-6-PHENETHYL-PYRAN-2-ONE;4-Hydroxy-6-phenethyl-2H-pyran-2-one
• CAS NO: 33253-32-6
• Molecular Formula: C₁₃H₁₂O₃
• Molecular Weight: 216.23
• Mol File: 33253-32-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-HYDROXY-6-PHENETHYL-PYRAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-6-PHENETHYL-PYRAN-2-ONE(33253-32-6)
• EPA Substance Registry System: 4-HYDROXY-6-PHENETHYL-PYRAN-2-ONE(33253-32-6)

Safety Data

• Hazardous Substances Data: 33253-32-6(Hazardous Substances Data)

Usage

General Description

4-HYDROXY-6-PHENETHYL-PYRAN-2-ONE is a chemical compound with a molecular formula C12H12O3. It is a natural flavoring substance that is often used in the food and beverage industry as an artificial flavoring agent. It is commonly found in baked goods, confectionery products, and beverages due to its sweet, caramel-like aroma. 4-HYDROXY-6-PHENETHYL-PYRAN-2-ONE is also used in the production of fragrances and perfumes due to its pleasant scent. Additionally, it has been studied for its potential antioxidant and antimicrobial properties, making it a versatile and useful compound in various industries.

Upstream product

• 675-10-5 4-hydroxy-6-methyl-2-pyron 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 2021-28-5 ethyl dihydrocinnamate 
• 3155-51-9 7,8-dihydro-4-methoxy-6-styryl-2H-pyran-2-one 

Downstream Products

• 158200-29-4 3-(α-ethylbenzyl)-6-phenethyl-4-hydroxy-2H-pyran-2-one 
• 162169-82-6 3-(α-cyclopropyl-meta-(4-cyanophenylsulfonylamino)benzyl)-6-(α-ethylphenethyl)-4-hydroxy-2H-pyran-2-one 
• 1642145-09-2 4-{1-[(tert-butyldimethylsilanyloxy)methyl]propoxy}-6-(2-phenylethyl)-2-pyrone 
• 1259312-69-0 9-phenethylbenzofuro[3,2-c]-2-pyrone 
• 1259312-82-7 4-(2-iodophenoxy)-6-phenethyl-2-pyrone 
• 1259313-10-4 4-bromo-6-phenethyl-2-pyrone 
• 162170-49-2 3-(α-cyclopropyl-meta-(benzyloxycarbonylamino)benzyl)-6-(α-ethyl-phenethyl)-4-hydroxy-2H-pyran-2-one 
• 162174-72-3 3-(α-cyclopropyl-meta-aminobenzyl)-6-(α-ethyl-phenethyl)-4-hydroxy-2H-pyran-2-one 
• 357156-75-3 4-methoxy-6-(2-phenylethyl)-3-phenylsulfinylmethyl-2H-pyran-2-one 

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4-hydroxy-6-alkyl-2-pyrones as nucleophilic coupling partners in Mitsunobu reactions and oxa-Michael additions

Two mild and efficient strategies have been developed for the O-functionalisation of 4-hydroxy-6-alkyl-2-pyrones, by using them as nucleophilic partners in oxa-Michael additions and the Mitsunobu reaction. The reactions proceed in moderate to excellent yields on a range of substrates containing useful functionality. The reactions serve as practical and valuable synthetic methods to construct complex 2-pyronyl ethers, which are found embedded in a number of natural products.