33257-86-2

Basic information

• Product Name: (2-hydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone
• CAS NO: 33257-86-2
• Molecular Formula: C₁₄H₁₂O₄
• Molecular Weight: 244.2427
• Mol File: 33257-86-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 439.4°C at 760 mmHg
• Flash Point: 169.7°C
• Density: 1.296g/cm³
• Vapor Pressure: 2.48E-08mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: (2-hydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-hydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone(33257-86-2)
• EPA Substance Registry System: (2-hydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone(33257-86-2)

Safety Data

• Hazardous Substances Data: 33257-86-2(Hazardous Substances Data)

Usage

Description

(2-hydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone is a versatile organic compound with the molecular formula C15H12O4. It is composed of two hydroxyphenyl groups and a methanone group, known for its antioxidant and anti-inflammatory properties.
Used in Pharmaceutical Industry:
(2-hydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone is used as an active pharmaceutical ingredient for its potential role in the treatment of various medical conditions, including cancer and neurodegenerative diseases.
Used in Cosmetic Industry:
(2-hydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone is used as an ingredient in cosmetic products for its antioxidant and anti-inflammatory properties, contributing to skin health and protection.

Upstream product

• 41351-30-8 (4-hydroxyphenyl)(2,4-dimethoxyphenyl)methanone 
• 99-96-7 4-hydroxy-benzoic acid 
• 150-19-6 O-methylresorcine 
• 2237-36-7 4-methoxysalicylic acid 
• 108-95-2 phenol 

Downstream Products

• 33257-83-9 4-(4-hydroxyphenyl)-7-methoxy-3-phenyl-2H-chromen-2-one 
• 207278-56-6 4-(4-Acetoxyphenyl)-7-methoxy-3-(4-(trifluoromethyl)phenyl)coumarin 
• 1450604-25-7 7-(2-morpholinoethoxy)-4-(4-hydroxyphenyl)-3-phenyl-2H-chromen-2-one 
• 1450604-24-6 7-(2-bromoethoxy)-4-(4-hydroxyphenyl)-3-phenyl-2H-chromen-2-one 
• 1450604-33-7 7-(2-(diethylamino)ethoxy)-4-(4-(2-(diethylamino)ethoxy)phenyl)-3-phenyl-2Hchromen-2-one 
• 1450604-32-6 7-(2-(piperidin-1-yl)ethoxy)-4-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-phenyl-2Hchromen-2-one 
• 1450604-31-5 7-(2-(pyrrolidin-1-yl)ethoxy)-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-phenyl-2Hchromen-2-one 
• 1450604-23-5 7-(2-morpholinoethoxy)-4-(4-(2-morpholinoethoxy)phenyl)-3-phenyl-2H-chromen-2-one 
• 1450604-22-4 7-(2-bromoethoxy)-4-(4-(2-bromoethoxy)phenyl)-3-phenyl-2H-chromen-2-one 
• 1450604-29-1 7-(2-bromoethoxy)-3,4-bis(4-(2-bromoethoxy)phenyl)-2H-chromen-2-one 
• 33257-75-9 7-hydroxy-4-(4-hydroxyphenyl)-3-phenyl-2H-chromen-2-one 
• 1450604-28-0 7-hydroxy-3,4-bis(4-hydroxyphenyl)-2H-chromen-2-one 
• 1450604-36-0 7-(2-(diethylamino)ethoxy)-4-(4-hydroxyphenyl)-3-phenyl-2H-chromen-2-one 
• 1450604-35-9 7-(2-(piperidin-1-yl)ethoxy)-4-(4-hydroxyphenyl)-3-phenyl-2H-chromen-2-one 

Relevant articles and documents

Design, synthesis, and anti-tumor activities of novel triphenylethylene- coumarin hybrids, and their interactions with Ct-DNA

Novel triphenylethylene-coumarin hybrid derivatives containing different amounts of amino side chains were designed and synthesized in good yields under microwave radiation. The derivatives 5b-d which possessed two amino side chains (except morpholinyl) showed a broad-spectrum and good anti-proliferative activity against five tumor cells and low cytotoxicity in osteoblast. UV-vis, fluorescence, and circular dichroism (CD) spectroscopies and thermal denaturation exhibited that compounds 10c, 5c, and 13c bearing amino side chain (except morpholinyl) on 4-phenyl had significant interactions with Ct-DNA by the intercalative mode of binding. Structure-activity relationships (SARs) analysis suggested that the amino alkyl chain would play an important role both in the compounds against tumor cells proliferation and their interactions with DNA.

Synthetic polystyrene resin and its use in solid phase peptide synthesis

A synthetic resin based on a polystyrene that can be used as a support for solid phase peptide synthesis and that has been cross-linked with from 0 to 5 mol % of divinyl benzene, characterized in that it has been substituted at benzene rings of its skelet