3327-27-3 Usage
Description
2-(pyridin-3-yl)-4H-chromen-4-one, also known as 3-(pyridin-3-yl)coumarin, is a chemical compound with a molecular formula of C15H9NO2 and a molecular weight of 235.24 g/mol. It belongs to the class of coumarin derivatives, which are known for their diverse biological activities. 2-(pyridin-3-yl)-4H-chromen-4-one is characterized by the presence of a pyridine and coumarin moiety in its structure, which contribute to its unique chemical and biological properties. This makes 2-(pyridin-3-yl)-4H-chromen-4-one a subject of interest in medicinal and bioanalytical research.
Uses
Used in Pharmaceutical Industry:
2-(pyridin-3-yl)-4H-chromen-4-one is used as a potential therapeutic agent for various health conditions due to its anti-inflammatory, anti-cancer, and anti-microbial properties. Its ability to modulate biological processes and target specific pathways makes it a promising candidate for the development of new drugs.
Used in Bioanalytical Research:
2-(pyridin-3-yl)-4H-chromen-4-one is used as a fluorescent probe for detecting metal ions in biological systems. Its unique chemical properties allow it to interact with metal ions, making it a valuable tool for researchers in the field of bioanalysis and environmental monitoring.
Used in Material Science:
2-(pyridin-3-yl)-4H-chromen-4-one is used as a component in the development of new materials with potential applications in various industries. Its chemical structure and properties can be exploited to create materials with specific characteristics, such as improved stability or enhanced reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 3327-27-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,2 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3327-27:
(6*3)+(5*3)+(4*2)+(3*7)+(2*2)+(1*7)=73
73 % 10 = 3
So 3327-27-3 is a valid CAS Registry Number.
3327-27-3Relevant articles and documents
Thallium(III) p-tosylate-mediated oxidative [1,2] rearrangement of 2-naphthyl and 2-heteroarylchromanones
Kurapati, Chidvilas,Muthukrishnan, Murugan,Singh, Om V.,Gundla, Rambabu
, p. 172 - 177 (2021/10/29)
A practical and effective approach towards the synthesis of 3-heteroaryl-4H-chromen-4-ones by the oxidative [1,2] rearrangement of the respective 2-heteroaryl chroman-4-ones using thallium(III) p-tosylate is presented. The oxidative rearrangement of α- an
Synthesis and antiviral activity of 2-aryl-4H-chromen-4-one derivatives against Chikungunya virus
Badavath, Vishnu N.,Jadav, Surender S.,Pastorino, Boris,De Lamballerie, Xavier,Sinha, Barij N.,Jayaprakash, Venkatesan
, p. 1019 - 1024 (2016/11/25)
A series of nineteen 2-aryl-4H-chromen-4-one derivatives 2a-2s were synthesized and evaluated for their antiviral activity against Chikungunya virus (LR2006-OPY1) in Vero cell culture by CPE reduction assay. Three compounds 2a, 2b and 2g, were found to be active at concentration of (IC50) 0.44 μM, 0.45 μM and 2.02 μM, respectively. Compounds having heterocyclic ring 2a and 2b at the 2nd position of the chromenone were found to be potent inhibitor of ChikV. Cytotoxicity studies were performed using Vero cell culture, compounds 2a and 2b exhibited SI of ≥100. Molecular docking simulation has been carried out to understand the possible mechanism of action.
Highly efficient synthesis of flavones: Via Pd/C-catalyzed cyclocarbonylation of 2-iodophenol with terminal acetylenes
Zhu, Fengxiang,Li, Yahui,Wang, Zechao,Wu, Xiao-Feng
, p. 2905 - 2909 (2016/05/24)
A highly efficient and selective Pd/C-catalyzed ligand-free cyclocarbonylation reaction for the synthesis of flavones has been developed. Various flavone derivatives were isolated in excellent yields with excellent functional group tolerances. Additionally, catalyst reuse experiments were performed successfully as well.
