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3-Methoxy-17-methylmorphinan-4-ol, also known as codeine, is a naturally occurring opiate alkaloid found in the opium poppy plant. It is a derivative of morphine and is used as an analgesic to treat mild to moderate pain, as well as a cough suppressant. Codeine works by binding to the mu-opioid receptors in the brain, which reduces the perception of pain and suppresses the cough reflex. It is commonly prescribed in combination with other medications, such as acetaminophen or ibuprofen, to enhance its pain-relieving effects. However, it is important to note that codeine has the potential for abuse and addiction, and its use should be carefully monitored by healthcare professionals.

3327-79-5

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3327-79-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3327-79-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,2 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3327-79:
(6*3)+(5*3)+(4*2)+(3*7)+(2*7)+(1*9)=85
85 % 10 = 5
So 3327-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H25NO2/c1-19-10-9-18-8-4-3-5-13(18)14(19)11-12-6-7-15(21-2)17(20)16(12)18/h6-7,13-14,20H,3-5,8-11H2,1-2H3/t13-,14-,18-/m0/s1

3327-79-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Tetrahydrodesoxycodeine

1.2 Other means of identification

Product number -
Other names (-)-Tetrahydrodesoxykodein

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3327-79-5 SDS

3327-79-5Relevant academic research and scientific papers

MORPHAN AND MORPHINAN ANALOGUES, AND METHODS OF USE

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Page/Page column 74, (2014/12/12)

The present application relates to analogues of morphan and morphinan, compositions thereof, and methods for treating a disease or condition comprising administering an effective amount of the compounds or compositions to a subject in need thereof.

Synthesis and pharmacological evaluation of 6,7-indolo/thiazolo-morphinans - Further SAR of levorphanol

Zhang, Ao,Li, Fuying,Ding, Chunyong,Yao, Qizhen,Knapp, Brian I.,Bidlack, Jean M.,Neumeyer, John L.

, p. 2747 - 2751 (2008/02/07)

To further extend the structure-activity relationships of levorphanol, two series of novel morphinans were prepared by incorporation of an indole or aminothiazole fragment to the hexyl ring (ring C) in levorphanol. Such morphinans differed from previously reported ligands in that such indole- or aminothiazole-containing morphinans displayed enhanced binding affinity to the δ opioid receptor, while the affinity to κ and μ receptors was slightly reduced.

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