333-42-6

Basic information

• Product Name: thiophosphoric acid O,O'-diethyl ester S-(4-fluorophenyl) ester
• Synonyms: thiophosphoric acid O,O'-diethyl ester S-(4-fluorophenyl) ester
• CAS NO: 333-42-6
• Molecular Weight: 264.258
• Mol File: 333-42-6.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: thiophosphoric acid O,O'-diethyl ester S-(4-fluorophenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: thiophosphoric acid O,O'-diethyl ester S-(4-fluorophenyl) ester(333-42-6)
• EPA Substance Registry System: thiophosphoric acid O,O'-diethyl ester S-(4-fluorophenyl) ester(333-42-6)

Safety Data

• Hazardous Substances Data: 333-42-6(Hazardous Substances Data)

Upstream product

• 371-42-6 4-Fluorothiophenol 
• 814-49-3 diethyl chlorophosphate 
• 762-04-9 phosphonic acid diethyl ester 
• 1146127-04-9 4-fluoro-2,4,6-trimethyldiphenyliodonium trifluoromethanesulfonate 
• 459-45-0 4-fluorobenzenediazonium tetrafluoroborate 
• 405-31-2 bis(4-fluorophenyl)disulfide 
• 1765-93-1 4-fluoroboronic acid 
• 1535-35-9 4-fluorobenzenesulphenyl chloride 
• 122-52-1 triethyl phosphite 
• 371-40-4 4-fluoroaniline 

Downstream Products

• 1062609-62-4 4-fluorophenyltetrafluoro-λ⁶-sulfanyl chloride 
• 371-42-6 4-Fluorothiophenol 
• 867-17-4 diethyl methyl phosphate 

Relevant articles and documents

Benign synthesis of thiophosphates, thiophosphinates and selenophosphates in neat condition using N-chalcogenoimides as the source of electrophilic sulfur/selenium

A neat reaction protocol has been developed for synthesis of thiophosphate, thiophosphinate and selenophosphate compounds. N-chalcogenoimides have been used for chalcogenylation of P(O)H moieties of various H-phosphonates under solvent, catalyst and base free condition at room temperature in aerial atmosphere. Both S-aryl and S-alkyl phosphorothioate compounds were prepared by this method in good yields. Selenophosphates were also synthesized using N-(phenylseleno)phthalimide under solvent free condition.

Electrochemically driven synthesis of phosphorothioates from trialkyl phosphites and aryl thiols

A facile and elegant protocol for synthesis of phosphorothioates from trialkyl phosphites and aryl thiols via indirect electrochemical oxidation mediated by KI has been successfully developed. KI as a redox mediator, enabled the reaction of trialkyl phosp

Synthetic method of thiophosphate compound

The invention discloses a synthetic method of a phosphorothioate compound. The preparation method comprises the following steps: with thiol as a reaction substrate and trichloroisocyanuric acid (TCCA)as an accelerant, reacting the reaction substrate and the accelerant in an organic solvent at normal temperature and normal pressure for 10-20 minutes, then adding phosphite triester, continuing reacting for 10-20 minutes, and after the reaction is finished, carrying out separation treatment to obtain the phosphorothioate compound. According to the synthesis method disclosed by the invention, thereaction is carried out at normal temperature and normal pressure without special requirements; reaction time is short; and reaction substrate universality is good.