33322-66-6

Upstream product

• 16331-45-6 p-ethylbenzoyl chloride 
• 506-59-2 N,N-dimethylammonium chloride 
• 2386-64-3 ethylmagnesium chloride 
• 14062-80-7 N,N-dimethyl-4-chlorobenzamide 
• 7463-22-1 N,N-Dimethyl-p-chlorobenzenesulfonamide 

Downstream Products

• 1008119-09-2 4-acetyl-N,N-dimethylbenzamide 
• 1325242-68-9 4-(α-acetoxyethyl)-N,N-dimethylbenzamide 
• 1325242-78-1 4-(α-acetoxyethyl)-N-methylbenzamide 
• 1325242-73-6 4-(α-benzoyloxyethyl)-N,N-dimethylbenzamide 

Relevant academic research and scientific papers

Iron-Catalyzed C(sp2)-C(sp3) Cross-Coupling of Chlorobenzenesulfonamides with Alkyl Grignard Reagents: Entry to Alkylated Aromatics

Alkylated benzosulfonamides are compounds of high importance in organic synthesis, including the production of pharmaceuticals, agrochemicals, and plasticizers. We report the iron-catalyzed C(sp2)-C(sp3) cross-coupling of chlorobenzosulfonamides with alkyl Grignard reagents under mild and sustainable conditions. Electronically and sterically varied benzosulfonamides as well as challenging alkyl organometallics containing β-hydrogen afford alkylated benzosulfonamides in high to excellent yields. Sulfonamide represents the most reactive activating group for iron-catalyzed cross-coupling. The process affords alkylated benzenesulfonamides poised for medicinal chemistry applications and traceless reductive cleavage.

Iron-Catalyzed C(sp2)?C(sp3) Cross-Coupling of Chlorobenzamides with Alkyl Grignard Reagents: Development of Catalyst System, Synthetic Scope, and Application

Direct preparation of alkylated amide-derivatives by cross-coupling chemistry using sustainable protocols is challenging due to sensitivity of the amide functional group to reaction conditions. Herein, we report the synthesis of alkyl-substituted amides b

Amidrazones and their use as pesticides

This invention relates to amidrazones, insecticidal amidrazone compositions, and methods of using such compositions.