3333-14-0

Basic information

• Product Name: 2,3-diphenylpropiononitrile
• Synonyms: 2,3-diphenylpropiononitrile;2,3-Diphenylpropanenitrile;α,β-Diphenylpropiononitrile
• CAS NO: 3333-14-0
• Molecular Formula: C₁₅H₁₃N
• Molecular Weight: 207.27042
• EINECS: 222-064-0
• Mol File: 3333-14-0.mol
• Article Data: 66

Chemical Properties

• Melting Point: 58 °C
• Boiling Point: 330.8°Cat760mmHg
• Flash Point: 162.7°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.000162mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 2,3-diphenylpropiononitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diphenylpropiononitrile(3333-14-0)
• EPA Substance Registry System: 2,3-diphenylpropiononitrile(3333-14-0)

Safety Data

• Hazardous Substances Data: 3333-14-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 7, p. 1509, 1966 DOI: 10.1016/0005-2760(66)90119-6

InChI:InChI=1/C15H13N/c16-12-15(14-9-5-2-6-10-14)11-13-7-3-1-4-8-13/h1-10,15H,11H2

Upstream product

• 5424-86-2 2,3-diphenylsuccinonitrile 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 16610-80-3 (E)-2,3-diphenylacrylonitrile 
• 140-29-4 phenylacetonitrile 
• 100-51-6 benzyl alcohol 
• 7472-97-1 (S)-2.3-diphenyl-propionic acid amide 
• 2450-55-7 diphenyl fumarodinitrile 
• 141-52-6 sodium ethanolate 
• 6362-63-6 ethyl 3-cyano-3-phenylpyruvate 
• 6114-57-4 (Z)-2,3-diphenylacrylonitrile 
• 100-42-5 styrene 
• 7677-24-9 trimethylsilyl cyanide 
• 62-53-3 aniline 
• 945-51-7 1,1'-sulfinylbisbenzene 

Downstream Products

• 94897-34-4 3,4-diphenyl-2-butanone 
• 7472-97-1 2,3-diphenylpropionamide 
• 94942-89-9 2,3-diphenylpropanoic acid 
• 56751-36-1 2,3-dibenzyl-2,3-diphenyl-succinonitrile 
• 5415-80-5 2,3-diphenylpropan-1-amine 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 3333-16-2 2-benzyl-2,3-diphenyl-propionitrile 
• 101890-02-2 3-cyano-3,4-diphenyl-butyric acid ethyl ester 
• 62567-78-6 2-(5-Chloro-2-nitro-phenyl)-2,3-diphenyl-propionitrile 
• 62567-77-5 2-(3-Chloro-4-nitro-phenyl)-2,3-diphenyl-propionitrile 
• 62567-79-7 2-[5-(1-Cyano-1,2-diphenyl-ethyl)-2-nitro-phenyl]-2,3-diphenyl-propionitrile 
• 119819-36-2 2-Benzyl-3-(2-bromo-cyclopropyl)-2-phenyl-propionitrile 
• 451-40-1 phenyl benzyl ketone 
• 64133-86-4 2-(4-Benzoyl-2-chloro-phenyl)-2,3-diphenyl-propionitrile 

Relevant articles and documents

PHOTOCHEMICAL REACTIONS OF ARENECARBONITRILES WITH ALIPHATIC AMINES. 1. EFFECT OF ARENE STRUCTURE ON AMINYL VS. alpha -AMINOALKYL RADICAL FORMATION.

The photochemical reactions of several singlet arenecarbonitriles with aliphatic amines have been investigated. The reactions of 9-phenanthrenecarbonitrile with diethylamaine and its N- and alpha -C deuterated derivatives result in exclusive N-H atom transfer to yield the diethylaminyl and 9-cyano-9,10-dihydrophenanthren-9-yl radicals in benzene solution. Increased solvent polarity results in the formation of both diethylaminyl and 1-(ethylamino)ethyl radical. Similar results are obtained with 9-anthracenecarbonitrile. The competition between aminyl vs. alpha -aminoalkyl radical formation in this and other reactions is reviewed. Aminyl radical formation is characteristic of relatively nonpolar heteroexcimers in which hydrogen bonding may favor N-H transfer. Pure charge-transfer exciplexes, like alkoxyl radicals, yield predominantly the thermodynamically more stable alpha -aminoalkyl radical.

Enantioselective Arylcyanation of Styrenes via Copper-Catalyzed Radical Relay?

The first copper-catalyzed enantioselective arylcyanation of styrenes has been developed using readily available anilines as aryl radical precursors under mild conditions, which enables easy access to chiral 2,3-diaryl propionitriles with moderate to good

Rapid and Simple Access to α-(Hetero)arylacetonitriles from Gem-Difluoroalkenes

A scalable cyanation of gem-difluoroalkenes to (hetero)arylacetonitrile derivatives was developed. This strategy features mild reaction conditions, excellent yields, wide substrate scope, and broad functional group tolerance. Significantly, in this reacti

Catalyst for α alkylation of nitriles and uses thereof

The invention discloses a nitrile alpha-alkylation reaction catalyst and application thereof. The nitrile alkylation reaction catalyzed by pyridine-pyridine-imidazoline asymmetric pincerlike rutheniumcompounds has a reaction general formula shown in the specification, and in the general formula, a catalyst is a pyridine-pyridine-imidazoline asymmetric pincerlike ruthenium compound, R1 is aryl, and R2 is aryl or alkyl, wherein aryl is phenyl, p-methylphenyl, p-methoxyphenyl, p-chlorophenyl, thiophene and the like, and alkyl is n-butyl, phenylpropyl and the like. The synthesis method comprisesthe following synthesis steps: adding an asymmetric pincerlike ruthenium compound, an alkali, a nitrile compound and an alcohol into a solvent for reaction, and after the reaction is finished, conducting separating and purifying to obtain a corresponding target product. Alcohol is used as an alkylating reagent, generated water is a unique by-product, the method conforms to the ideas of atom economy and environmental friendliness, and meanwhile, the method has the advantages of use of a catalytic amount of alkali, short reaction time, economy and the like.