333310-16-0Relevant academic research and scientific papers
L-Proline triflate as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles
Li, Jianjun,Lin, Shouwang,Dai, Jiajia,Su, Weike
, p. 196 - 199 (2010)
L-Proline triflate has been used as an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles in good yields. The benefit of this approach is its operational simplicity and the catalyst can be easily recovered and reused without any loss of activity.
Modular synthesis of tetrasubstituted imidazoles and trisubstituted oxazoles by aldimine cross-coupling
Kison, Coralie,Opatz, Till
experimental part, p. 843 - 845 (2009/06/28)
A study was conducted to demonstrate the synthesis of tetrasubstituted imidazoles and trisubstituted oxazoles by aldimine cross-coupling reaction. The method involved 1,2-addition of easily available deprotonated N-monosubstituted α-aminotitriles to aldim
