333310-17-1Relevant articles and documents
New Method for Synthesis of Multi-substituted Imidazoles
Marzouk, Adel A.,Mohamed, Shaaban K.,Aljohani, Enas T.,Abdelhamid, Antar A.
, p. 1775 - 1782 (2018/07/25)
Here, we reported two methods for the synthesis of multi-substituted imidazoles, firstly via four-component cyclocondensation reaction of benzil, aliphatic amines (allylamine or pentylamine), and aromatic aldehyde and ammonium acetate. Using an ionic liqu
An efficient and one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by InCl3·3H2O
Das Sharma, Saikat,Hazarika, Parasa,Konwar, Dilip
, p. 2216 - 2220 (2008/09/18)
InCl3·3H2O was found to be a mild and effective catalyst for the efficient, one-pot, three component synthesis of 2,4,5-trisubstituted imidazoles at room temperature. Moreover, the utility of this protocol was further explored conveniently for the one-pot, four component synthesis of 1,2,4,5-tetrasubstituted imidazoles in high yields.