333405-44-0

Upstream product

• 333405-32-6 {(1S)-1-[(4R)-4-(3-hydroxy-propyl)-5-oxo-tetrahydro-furan-(2S)-2-yl]-2-phenyl-ethyl} carbamic acid tert-butyl ester 
• 137281-77-7 {(1S)-1-[(4R)-4-allyl-5-oxo-tetrahydro-furan-(2S)-2-yl]-2-phenyl-ethyl} carbamic acid tert-butyl ester 
• 133333-27-4 tert-butyl (1S)-1-[(2S)-5-oxotetrahydrofuran-2-yl]-2-phenylethylcarbamate 

Downstream Products

• 333405-50-8 [(1S)-1-{(1S)-1-[(4R)-4-(3-azido-propyl)-5-oxo-tetrahydro-furan-(2S)-2-yl]-2-phenyl-ethylcarbamoyl}-2-(trityl-carbamoyl)-ethyl]-carbamic acid benzyl ester 
• 333405-56-4 (2R)-2-(3-azido-propyl)-(5S)-5-[(2S)-2-benzyloxycarbonylamino-3-(trityl-carbamoyl)-propionylamino]-(4S)-4-(tert-butyl-dimethyl-silanyloxy)-6-phenyl-hexanoic acid 
• 333406-00-1 C₄₆H₄₆N₄O₇H₂SiC₆H₁₄P(C₆H₅)3 
• 333406-04-5 (5S)-5-[(2S)-2-benzyloxycarbonylamino-3-(trityl-carbamoyl)-propionylamino]-(4S)-4-(tert-butyl-dimethyl-silanyloxy)-(2R)-2-(3-N,N'-bis-t-boc-guanidino-propyl)-6-phenyl-hexanoic acid 

Relevant academic research and scientific papers

Synthesis of a tripeptide derivative containing the Phe-Arg hydroxyethylene dipeptide isostere.

The protected hydroxyethylene dipeptide isostere of Phe-Arg and the tripeptide derivative 1 were synthesized as components of potential peptidase inhibitors. Key to the success of these syntheses is selective rhodium-catalyzed hydroboration in the presenc