333458-88-1

Basic information

• Product Name: ethyl 1-[4-cyano-2-(2,6-dichlorophenylamino)-3-methyl-3H-benzimidazol-5-yl]-2-oxo-cyclopentanecarboxylate
• CAS NO: 333458-88-1
• Molecular Weight: 471.343
• Mol File: 333458-88-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 1-[4-cyano-2-(2,6-dichlorophenylamino)-3-methyl-3H-benzimidazol-5-yl]-2-oxo-cyclopentanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-[4-cyano-2-(2,6-dichlorophenylamino)-3-methyl-3H-benzimidazol-5-yl]-2-oxo-cyclopentanecarboxylate(333458-88-1)
• EPA Substance Registry System: ethyl 1-[4-cyano-2-(2,6-dichlorophenylamino)-3-methyl-3H-benzimidazol-5-yl]-2-oxo-cyclopentanecarboxylate(333458-88-1)

Safety Data

• Hazardous Substances Data: 333458-88-1(Hazardous Substances Data)

Upstream product

• 333458-84-7 ethyl 1-(2-cyano-3-methylamino-4-nitrophenyl)-2-oxo-cyclopentanecarboxylate 
• 333458-39-2 6-chloro-2-methylamino-3-nitrobenzonitrile 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 5866-98-8 2,6-dichloro-3-nitrobenzonitrile 
• 6590-95-0 2,6-dichlorophenylisothiocyanate 
• 333458-86-9 ethyl 1-(4-amino-2-cyano-3-methylaminophenyl)-2-oxo-cyclopentanecarboxylate 

Relevant articles and documents

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Isoquinolinone synthesis by SNAr reaction: A versatile route to imidazo[4,5-h]isoquinolin-9-ones

Reaction of 2-chlorobenzonitriles with β-ketoesters in an SNAr reaction, followed by cyclization in acid provides a versatile route to isoquinolones. Starting from 2,6-dichloro-3-nitrobenzonitrile 7, sequential displacement of the chlorines by