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18-Fluorooctadecanoic acid methyl ester, also known as F-FDG or 18F-FDG, is a radiolabeled chemical compound used in positron emission tomography (PET) imaging. It is a synthetic analog of glucose, where the hydroxyl group on carbon 2 has been replaced with a fluorine-18 isotope. This modification allows the compound to be detected by PET scanners, which can visualize the distribution of the tracer within the body. 18F-FDG is primarily used for diagnosing and monitoring various types of cancer, as cancer cells often have higher glucose metabolism than normal cells. By tracking the accumulation of 18F-FDG in tissues, physicians can identify areas of increased metabolic activity, which may indicate the presence of tumors or metastases. The compound is administered intravenously and is rapidly taken up by cells, providing valuable information for clinical decision-making in oncology.

463-29-6

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463-29-6 Usage

Type

Fluorinated derivative of octadecanoic acid methyl ester (stearic acid methyl ester)

Usage

Precursor in the synthesis of radiolabeled compounds

Application

Positron emission tomography (PET) imaging studies

Research focus

Development of new radiotracers for medical imaging

Specific application

Study of fatty acid metabolism and its role in diseases (e.g., cancer, cardiovascular disorders)

Key component

Fluorine atom

Role of fluorine

Provides necessary radioactivity for PET imaging applications

Check Digit Verification of cas no

The CAS Registry Mumber 463-29-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 463-29:
(5*4)+(4*6)+(3*3)+(2*2)+(1*9)=66
66 % 10 = 6
So 463-29-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H37FO2/c1-22-19(21)17-15-13-11-9-7-5-3-2-4-6-8-10-12-14-16-18-20/h2-18H2,1H3

463-29-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 18-fluorooctadecanoate

1.2 Other means of identification

Product number -
Other names 18-Fluor-octadecansaeure-methylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:463-29-6 SDS

463-29-6Downstream Products

463-29-6Relevant academic research and scientific papers

Omega-functionalized fatty acids, alcohols, and ethers via olefin metathesis

Zerkowski, Jonathan A.,Solaiman, Daniel K. Y.

experimental part, p. 1325 - 1332 (2012/09/10)

Methyl 17-hydroxy stearate was converted to methyl octadec-16-enoate using copper sulfate adsorbed on silica gel. This compound served as a useful substrate for the olefin metathesis reaction. As a result, several fatty acids with novel functional groups at the x-end were prepared: a glyceryl ether attached at the 18-carbon, an aromatic fatty acid from eugenol, and a ferrocenyl fatty acid. By employing the unsaturated fatty alcohol, other groups were introduced, namely the terminal fluoride, bromide, and iodide were prepared, as was a thiol derivative. The penultimate and omega olefins reported here should serve as building blocks that allow fatty acids to make a greater contribution to a range of emerging technological

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