3340-22-5Relevant academic research and scientific papers
Diverse tandem cyclization reactions of o -cyanoanilines and diaryliodonium salts with copper catalyst for the construction of quinazolinimine and acridine scaffolds
Pang, Xinlong,Chen, Chao,Su, Xiang,Li, Ming,Wen, Lirong
supporting information, p. 6228 - 6231 (2015/01/09)
Two cyclization modes are realized to produce different nitrogen-containing heterocycles, i.e.; quinazolin-4(3H)-imines and acridines by assembling o-cyanoanilines and diaryliodonium salts via tandem reaction pathways.
Synthesis and?SAR study of?acridine, 2-methylquinoline and?2-phenylquinazoline analogues as?anti-prion agents
Cope,Mutter,Heal,Pascoe,Brown,Pratt,Chen
, p. 1124 - 1143 (2007/10/03)
Transmissible spongiform encephalopathies (TSEs) are thought to arise from aggregation of a protease resistant protein denoted PrPSc, which is a misfolded isoform of the normal cellular prion protein PrPC. Using virtual high-throughp
Gas-phase cyclisation reactions of 1-(2-arylaminophenyl)alkaniminyl radicals
Leardini, Rino,McNab, Hamish,Nanni, Daniele,Parsons, Simon,Reed, David,Tenan, Anton G.
, p. 1833 - 1838 (2007/10/03)
Flash vacuum pyrolysis (FVP) of the oxime ethers 9-11 at 650°C (10-2-10-3 Torr) gives products such as the nitrile 17, carbazoles 19 and 20 and acridines 18 and 21 derived from the corresponding iminyl radicals 13-15. The mechanism proposed for the formation of the acridines involves a key hydrogen abstraction by the iminyl of the adjacent N-H atom. When this route is blocked by an N-methyl group, as in 12, alternative cyclisations ensue, yielding the dihydroquinazoline 26 (via another hydrogen abstraction process) and the benzimidazole 25 (via an iminyl-imidoyl interconversion).
SPECTRAL AND LUMINESCENT PROPERTIES OF 9-ARYLAMINOACRIDINES
Budyka, M. F.,Fatkulbayanov, R. M.
, p. 1075 - 1080 (2007/10/02)
A study has been made of the influence of electronic and steric factors of the aromatic substituent in 9-arylaminoacridines on the behavior of these compounds when subjected to light quanta or electron impact.It has been shown that the introduction of don
