33402-89-0Relevant academic research and scientific papers
Amide Bond Formation via Aerobic Photooxidative Coupling of Aldehydes with Amines Catalyzed by a Riboflavin Derivative
Hassan Tolba, Amal,Krupi?ka, Martin,Chudoba, Josef,Cibulka, Radek
supporting information, p. 6825 - 6830 (2021/09/11)
We report an effective, operationally simple, and environmentally friendly system for the synthesis of tertiary amides by the oxidative coupling of aromatic or aliphatic aldehydes with amines mediated by riboflavin tetraacetate (RFTA), an inexpensive organic photocatalyst, and visible light using oxygen as the sole oxidant. The method is based on the oxidative power of an excited flavin catalyst and the relatively low oxidation potential of the hemiaminal formed by amine to aldehyde addition.
Zinc-mediated allylation and alkylation of aminals in the presence of TMSCl and diisopropylamine
Hatano, Bunpei,Nagahashi, Keita,Kijima, Tatsuro
supporting information; body text, p. 9188 - 9191 (2009/04/11)
(Chemical Equation Presented) An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, α-bromoacetate, and α-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine.
Aminal Exchange
Katritzky, Alan R.,Yannakopoulou, Konstantina,Lang, Hengyuan
, p. 1867 - 1870 (2007/10/02)
Reactions of N-(α-benzotriazolylalkyl)-N,N-dialkylamines with the dialkylamine corresponding to the dialkylamino substituent afford symmetrical aminals in good yields.Treatment with other dialkylamines gives mixtures of the unsymmetrical and the two symme
Synthesis and Reaction of Methylbenzoquinolizinium Salts
Arai, Sadao,Yamazaki, Masuo,Hida, Mitsuhiko
, p. 1073 - 1078 (2007/10/02)
All isomers of (monomethyl)benzoquinolizinium salts including five new monomethyl derivatives were prepared by photocyclization, sulfur extrusion, or cyclodehydration reaction, and their aldol-type condensation was examined.The 2- and 4-methyl derivati
Trimethylsilylamines III: mise en evidence du compose d'addition sur les aldehydes; preparation d'aminals et de β-dialkylamino β-arylesters en milieu aprotique
Aube, Philippe,Christot, Isabelle,Combret, Jean-Claude,Klein, Jean-Louis
, p. 1009 - 1014 (2007/10/02)
Dialkylaminotrimethylsilanes react with aromatic aldehydes using trimethylsilyltriflate and tetrabutylammonium fluoride as catalysts and lead quantitatively to the corresponding aminals in aprotic media.The intermediate silylated hemiaminal can be characterized in many cases, mainly with pyridinecarbaldehydes.Aminals are obtained from aliphatic aldehydes using fluoride ion as catalyst.A one-pot synthesis of some β-dialkylamino β-arylesters from these reagents is described.
