3768-56-7

Usage

Uses

N-PiperidinoTrimethylsilane has been used in the synthesis of novel hydroborating agents.

InChI:InChI=1/C8H19NSi/c1-10(2,3)9-7-5-4-6-8-9/h4-8H2,1-3H3

Upstream product

• 110-89-4 piperidine 
• 75-77-4 chloro-trimethyl-silane 
• 333361-87-8 bis(trimethylsilyl) [2-(2-furyl)-1-(trimethylsilyloxycarbonyl)ethyl]phosphonite 
• 27325-49-1 1-piperidinylphosphorous dichloride 
• 333364-16-2 bis(trimethylsilyl) 2-(2-furyl)ethylphosphonite 

Downstream Products

• 107-46-0 Hexamethyldisiloxane 
• 33402-83-4 dipiperidinomethyl-2 furanne 
• 33402-84-5 di(piperidino)-2-thienylmethane 
• 880-09-1 di(N-piperidinyl)methane 
• 55591-37-2 1,1'-((4-chlorophenyl)methylene)dipiperidine 
• 2603-09-0 N-(4-chlorophenyl)-N',N'-(1,5-pentamethylenediyl)urea 
• 2538-76-3 1,1'-benzylidenedipiperidine 
• 33402-89-0 α,α-bis(piperidyl)-4-methoxytoluene 
• 70243-82-2 phenyl-(2-(piperidin-1-yl)-phenyl)-methanol 
• 32552-29-7 2-phenyl-6-piperidin-1-yl-[1,3,5]oxadiazin-4-one 
• 110-89-4 piperidine 
• 164653-03-6 5-Chloro-2-(piperidinocarbonylamino)benzoylguanidine 
• 164653-04-7 2-(Piperidinocarbonylamino)benzoylguanidine 
• 100632-34-6 N-benzoyl-N'-(piperidine-1-carbonyl)-hydrazine 

Relevant academic research and scientific papers

Preparation, Characterization, and Reactivity of Aliphatic Amino Iodane(III) Reagents

The preparation of a new class of aliphatic amino iodane(III) reagents has been realized with the N-TMS?amine and acetoxybenziodazole participated in the formation of N?I bond. The amino-containing iodane(III) reagent 2 d was characterized by single-crystal X-ray diffraction, which revealed the expected hypervalent iodane distorted T-shaped geometry. A practical copper-catalyzed, directed electrophilic amination of aryl amines employing amino-iodane(III) as amination agents was disclosed that proceeded smoothly without external additives.

2,4,6-Triphenylphosphinine and 2,4,6-triphenylposphabarrelene revisited: Synthesis, reactivity and coordination chemistry

The synthesis of 2,4,6-triphenylphosphinine has been revisited and a general protocol for the preparation of such low-coordinate phosphorus compounds in good to excellent yields could be established. This allows to investigate several aspects of the chemistry of 2,4,6-triarylphosphinine, such as the reaction with in situ generated benzyne to give 2,4,6-triphenylphosphabarrelene. The corresponding 2,4,6-triphenylphosphabarrelene-selenide could be characterized crystallographically for the first time and the structural and electronic properties of this cage-compound in comparison to classical triarylphosphines could be evaluated. Moreover, [(L)W(CO)5)] complexes of both 2,4,6-triphenylphosphinine and 2,4,6-triphenylphosphabarrelene were prepared and characterized by means of X-ray crystallography. This allowed for the first time a direct structural comparison of these related phosphorus compounds, coordinated to the same metal fragment.

Three-component coupling of arynes, aminosilanes, and aldehydes

A three-component coupling of arynes, aminosilanes, and aldehydes enables diverse amino and hydroxymethyl groups to be incorporated directly into 1,2-positions of aromatic rings.

Clean nitrations: Novel syntheses of nitramines and nitrate esters by nitrodesilylation reactions using dinitrogen pentoxide (N2O5)

In this novel nitration method dinitrogen pentoxide (N2O5) in an inert solvent is used as the nitrating agent, thereby removing the need for strong acids as the reaction medium. The N2O5 cleaves heteroatom-silicon bonds, in silylamines and silyl ethers respectively, to yield the desired energetic groupings (nitramines or nitrate esters respectively) without liberation of acids which would occur with conventional substrates (amines or alcohols). These nitrodesilylation reactions proceed cleanly and in good yield, and the scope of the reaction is illustrated by 29 examples, some of which produce high energy compounds, notably plasticisers and an energetic polymer precursor. These reactions are therefore potentially clean nitrations for the manufacture of energetic compounds which will minimise the impact of this activity on the environment in the future.

A Simple and Highly Diastereoselective One-Pot Synthesis of Mannich-Bases

A convenient one-pot procedure for the synthesis of β-amino ketones 5 from economical shelf reagents is described. Iminium salts 3 are generated in virtually quantitative yields from secondary amines 1 and aldehydes 2 mediated by NaI/Me3SiCl/NEt3. Subsequently, the salts 3 are used for the in situ aminoalkylation of enamines 4. The method provides the Mannich bases 5 in high yields and excellent diastereoselectivities (>96 % ds). It can also be applied for the aminoalkylation of other nucleophiles such as imines or electron-rich aromatic compounds.

Studies on organophosphorus compounds XLIX. An improved method for the preparation of 2,5-disubstituted 1,3,4-thiadiazoles and 1,3,4-thiadiazole-2(3H)-thiones

The reaction of 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide (LR) with N,N'-diacylhydrazines and N-acyl-N'-ethoxycarbonyl hydrazines has been investigated.It is shown that 2,5-disubstituted-1,3,4-thiadiazoles and 5-phenyl-1,3,4-thiadiazole-2(3H)-thione are produced in good yields.However, in the case of N-acetyl-N'-ethoxycarbonylhydrazine a 2,3-dihydro-1,3,4,2-thiadiazaphosphole, X, is formed.The fragmentation patterns in the mass spectra of simple 2,5-disubstituted 1,3,4,-thiadiazoles, IIIa-f, are described.

SOLUTION SYNTHESIS OF FULLY PROTECTED THYMIDINE DIMERS USING VARIOUS PHOSPHORAMIDITES

The synthesis of thymidine-3'-phosphoramidites of various amines and their use in the solution synthesis of fully protected thymidine dimers in high yields is desribed.