334025-76-2Relevant academic research and scientific papers
Synthesis and structure-activity relationship of diarylamide urea derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells.
Ogita, Haruhisa,Isobe, Yoshiaki,Takaku, Haruo,Sekine, Rena,Goto, Yuso,Misawa, Satoru,Hayashi, Hideya
, p. 1865 - 1871 (2002)
A series of diarylamide urea derivatives were synthesized and evaluated for their inhibitory activities against human coronary artery smooth muscle cells (SMCs) and human coronary artery endothelial cells (ECs). Compound 2o was superior to the lead compound, Tranilast, in terms of its potency of the inhibitory activity and cell selectivity.
