33421-24-8Relevant articles and documents
Dynamic Kinetic Resolution of Alcohols by Enantioselective Silylation Enabled by Two Orthogonal Transition-Metal Catalysts
Oestreich, Martin,Seliger, Jan
supporting information, p. 247 - 251 (2020/10/29)
A nonenzymatic dynamic kinetic resolution of acyclic and cyclic benzylic alcohols is reported. The approach merges rapid transition-metal-catalyzed alcohol racemization and enantioselective Cu-H-catalyzed dehydrogenative Si-O coupling of alcohols and hydrosilanes. The catalytic processes are orthogonal, and the racemization catalyst does not promote any background reactions such as the racemization of the silyl ether and its unselective formation. Often-used ruthenium half-sandwich complexes are not suitable but a bifunctional ruthenium pincer complex perfectly fulfills this purpose. By this, enantioselective silylation of racemic alcohol mixtures is achieved in high yields and with good levels of enantioselection.
Decarboxylative Arylation of Pyridine 1-Oxides and Anilides with Benzoic Acid via Palladium-Catalyzed C–H Functionalization
Dabiri, Minoo,Alavioon, Seyed Iman,Movahed, Siyavash Kazemi
, p. 1479 - 1487 (2019/02/19)
A novel method for the palladium-catalyzed decarboxylative ortho C–H bond arylation of pyridine 1-oxides and anilides with benzoic acids as aryl sources is described. The established methodology provides a direct approach for the synthesis of 2-arylpyridine 1-oxides and 2-aryl anilides in good isolated yields.
Palladium-catalyzed direct C-H arylation of pyridine N-oxides with potassium aryl- and heteroaryltrifluoroborates
Li, Mengli,Li, Xing,Chang, Honghong,Gao, Wenchao,Wei, Wenlong
supporting information, p. 2421 - 2426 (2016/03/01)
An efficient ligand-free Pd(OAc)2-catalyzed selective arylation of pyridine N-oxides using potassium (hetero)aryltrifluoroborates as coupling partners via C-H bond activation was achieved in the presence of TBAI. This approach has a broad subst
