33441-62-2

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 109-77-3 malononitrile 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 

Downstream Products

• 56526-37-5 5-(4-methoxy-phenyl)-thiazol-4-one 
• 41226-90-8 4-(4-chloro-phenyl)-2,3-bis-(4-methoxy-phenyl)-oxazolidine-5,5-dicarbonitrile 
• 59484-46-7 5-(4-methoxy-phenyl)-2-methyl-thiazol-4-one 
• 59484-43-4 5-(4-methoxy-phenyl)-2-phenyl-thiazol-4-one 
• 20714-90-3 4-Methoxymandelic acid 
• 110795-18-1 Acetic acid (E)-2-bromo-1-cyano-2-(4-methoxy-phenyl)-vinyl ester 
• 110795-10-3 Acetic acid (Z)-2-bromo-1-cyano-2-(4-methoxy-phenyl)-vinyl ester 
• 119420-51-8 Methanesulfonic acid (E)-2-bromo-1-cyano-2-(4-methoxy-phenyl)-vinyl ester 
• 119420-57-4 Methanesulfonic acid (Z)-2-bromo-1-cyano-2-(4-methoxy-phenyl)-vinyl ester 
• 127894-88-6 5-(4-Methoxy-phenyl)-3-p-tolyl-2-[(E)-p-tolylimino]-thiazolidin-4-one 
• 1404215-88-8 5-(4-methoxyphenyl)-3-phenyl-(2H,5H)-dihydrofuran-2,2-dicarbonitrile 
• 1404215-93-5 methyl 2,2-dicyano-5-(4-methoxyphenyl)-(2H,5H)-dihydrofuran-3-carboxylate 

Relevant academic research and scientific papers

Chiral C2-Symmetric Aminomethylbinaphthol as Synergistic Catalyst for Asymmetric Epoxidation of Alkylidenemalononitriles: Easy Access to Chiral Spirooxindoles

Chiral C2-symmetric 3,3′-bis((R,R)-2-naphthylethylaminomethyl)-(R)-binaphthol (AMB4) functions as an efficient organocatalyst for the asymmetric epoxidation of various alkylidenemalononitriles. The spiro-epoxyoxindole products obtained from isatilidenemal

Nucleophilic Reactivities of Bleach Reagents

The nucleophilicities of the oxidants hydroperoxide, hypochlorite, hypobromite, bromite, and peroxymonosulfate were determined by following the kinetics of their reactions with a series of benzhydrylium ions of known electrophilicity (E) in alkaline, aque

Epoxidation of vinyl cyanides by calcium hypochlorite under catalyst- and solvent-free conditions

In this paper, epoxidation of a wide range of alkenes by calcium hypochlorite (Ca(OCl)2) was investigated under catalyst- and solvent-free conditions. It was noticed that the highest yield was achieved with crushing, when the reaction was betwe

Solvation Accounts for the Counterintuitive Nucleophilicity Ordering of Peroxide Anions

The nucleophilic reactivities (N, sN) of peroxide anions (generated from aromatic and aliphatic peroxy acids or alkyl hydroperoxides) were investigated by following the kinetics of their reactions with a series of benzhydrylium ions (Ar2CH+) in alkaline aqueous solutions at 20 °C. The second-order rate constants revealed that deprotonated peroxy acids (RCO3?), although they are the considerably weaker Br?nsted bases, react much faster than anions of aliphatic hydroperoxides (ROO?). Substitution of the rate constants of their reactions with benzhydrylium ions into the linear free energy relationship lg k=sN(N+E) furnished nucleophilicity parameters (N, sN) of peroxide anions, which were successfully applied to predict the rates of Weitz–Scheffer epoxidations. DFT calculations with inclusion of solvent effects by means of the Integral Equation Formalism version of the Polarizable Continuum Model were performed to rationalize the observed reactivities.

Chemoenzymatic Synthesis of α-Cyano Epoxides by a Tandem-Knoevenagel-Epoxidation Reaction

An efficient lipase-mediated synthesis of α-cyano epoxides through a tandem-Knoevenagel-epoxidation reaction was explored for the first time. This method provides a green, mild, and convenient route for the synthesis of α-cyano epoxides; moreover, the app

Facile Epoxidation of Alumina-Supported Electrophilic Alkenes and Montmorillonite-Supported Electrophilic Alkenes with Sodium Hypochlorite

Alkenes gem-substituted by two electron-withdrawing substituents, dispersed on alumina or montmorillonite, are conveniently epoxided by sodium hypochlorite.A mixture of aldehyde and methylcyanoacetate or malononitrile, treated with alumina and sodium hypo