33454-16-9

Basic information

• Product Name: Benzenamine, 3-iodo-N,N-dimethyl-
• Synonyms: 3-iodo-N,N-dimethyl-aniline;N,N-dimethyl-3-iodoaniline;Benzenamine,3-iodo-N,N-dimethyl;3-iodo-N,N-dimetylaniline;3-Jod-N,N-dimethyl-anilin
• CAS NO: 33454-16-9
• Molecular Formula: C8H10IN
• Molecular Weight: 247.079
• Mol File: 33454-16-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 215-216 °C(Press: 190 Torr)
• Density: 1.652±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenamine, 3-iodo-N,N-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 3-iodo-N,N-dimethyl-(33454-16-9)
• EPA Substance Registry System: Benzenamine, 3-iodo-N,N-dimethyl-(33454-16-9)

Safety Data

• Hazardous Substances Data: 33454-16-9(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 626-01-7 3-Iodoaniline 
• 121-69-7 N,N-dimethyl-aniline 
• 74-88-4 methyl iodide 
• 16518-62-0 3-bromo-N,N-dimethylaniline 
• 64-18-6 formic acid 
• 645-00-1 m-iodonitrobenzene 
• 67-68-5 dimethyl sulfoxide 
• 88-74-4 2-nitro-aniline 
• 149-73-5 trimethyl orthoformate 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 873980-62-2 3-iodo-N,N-dimethyl-4-nitroso-aniline 
• 207789-57-9 2-iodo-4-(dimethylamino)benzaldehyde 
• 645389-09-9 2-(3-dimethylamino-phenyl)-6-methoxy-3,4-dihydro-2H-isoquinolin-1-one 
• 1310699-22-9 3-chloro-4-(2-iodo-4-(dimethylamino)phenyl)cyclobut-3-ene-1,2-dione 
• 1291063-32-5 4-bromo-3-iodo-N,N-dimethylaniline 

Relevant articles and documents

Meta-metallation of N,N-dimethylaniline: Contrasting direct sodium-mediated zincation with indirect sodiation-dialkylzinc co-complexation

Previously we reported that direct zincation of N,N-dimethylaniline by the mixed-metal zincate reagent 1 ((TMEDA)Na(TMP)(t-Bu)Zn(t-Bu)) surprisingly led to meta-metallation (zincation) of the aniline, as manifested in the crystalline complex 2 ((TMEDA)Na(

Scalable Synthesis of Acridinium Catalysts for Photoredox Deuterations

The continuous development of photocatalytic methods incentivizes the design of organic catalysts to complement the frequently used and precious polypyridyl transition metal systems. Herein, a scalable synthesis of suitable acridinium dyes and their appli

Efficient and Selective N-Methylation of Nitroarenes under Mild Reaction Conditions

Herein, we report a straightforward protocol for the preparation of N,N-dimethylated amines from readily available nitro starting materials using formic acid as a renewable C1 source and silanes as reducing agents. This tandem process is efficiently accomplished in the presence of a cubane-type Mo3PtS4 catalyst. For the preparation of the novel [Mo3Pt(PPh3)S4Cl3(dmen)3]+ (3+) (dmen: N,N′-dimethylethylenediamine) compound we have followed a [3+1] building block strategy starting from the trinuclear [Mo3S4Cl3(dmen)3]+ (1+) and Pt(PPh3)4 (2) complexes. The heterobimetallic 3+ cation preserves the main structural features of its 1+ cluster precursor. Interestingly, this catalytic protocol operates at room temperature with high chemoselectivity when the 3+ catalyst co-exists with its trinuclear 1+ precursor. N-heterocyclic arenes, double bonds, ketones, cyanides and ester functional groups are well retained after N-methylation of the corresponding functionalized nitroarenes. In addition, benzylic-type as well as aliphatic nitro compounds can also be methylated following this protocol.