33462-80-5

Usage

Uses

Used in Polymerization Industry:
(3-CHLOROPROPYL)DIPHENYLSULFONIUM TETRAFLUOROBORATE is used as a photoinitiator for the polymerization of acrylate and epoxy resins. It functions as a cationic photoinitiator upon exposure to UV light, generating a Lewis acid and a sulfuric acid that initiate the polymerization process of the resin.
Used in Organic Chemistry:
(3-CHLOROPROPYL)DIPHENYLSULFONIUM TETRAFLUOROBORATE is utilized in the synthesis of a variety of organic compounds, serving as a reagent in organic chemistry reactions. Its unique structure and reactivity contribute to the formation of diverse organic products.

InChI:InChI=1/C15H16ClS.BF4/c16-12-7-13-17(14-8-3-1-4-9-14)15-10-5-2-6-11-15;2-1(3,4)5/h1-6,8-11H,7,12-13H2;/q+1;-1

Upstream product

• 6940-76-7 1-iodo-3-chloro-propane 
• 139-66-2 diphenyl sulfide 
• 3384-04-1 3-chloropropyl phenyl ether 
• 627-30-5 1-chloro-3-hydroxypropane 
• 14104-20-2 silver tetrafluoroborate 

Downstream Products

• 33462-81-6 cyclopropyldiphenylsulfonium tetrafluoroborate 

Relevant academic research and scientific papers

CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS

The present disclosure describes novel IDO inhibitors and methods for preparing them. The pharmaceutical compositions comprising such IDO inhibitors and methods of using them for treating cancer, infectious diseases, and other disorders are also described

Synthesis of four novel natural product inspired scaffolds for drug discovery

Inspired by the novel spiro structures of a number of bioactive natural products such as the histrionicotoxins, a series of novel spiro scaffolds have been designed and robust syntheses developed. The scaffolds are ready-to-use building blocks and can be easily prepared on a 5-20 g scale. They contain two amino groups (one Boc-protected) and have been designed for ease of conversion to a lead generation library, using either amide formation or reductive amination procedures. The synthesis of the 1,9-diazaspiro[5.5]undecane and 3,7-diazaspiro[5.6]dodecane ring systems was achieved using RCM as the key step. A simple workup procedure is reported for the removal of highly colored ruthenium residues. The synthesis of the 1,8-diazaspiro[4.5]decane scaffold has been achieved using a bromine-mediated 5-endo cyclization of the corresponding 4-aminobutene intermediate under acidic conditions. This is the first example of this type of cyclization to be reported. A novel mechanism involving a bromine transfer reaction from an initially formed bromonium ion to a neighboring nitrogen atom is suggested as the reason for the failure of this type of reaction under "normal" bromination conditions. An unusual rearrangement of a 1-acyl-1,9-diazaspiro[5.5]undecane to the corresponding 9-acyl-1,9-diazaspiro[5.5]undecane is reported.

Synthesis of Fischer-Type (Alkoxy)carbene Complexes Using Diphenylsulfonium Salts with Functionalized Alkyl Groups

A new and general method for preparing Fischer-type alkoxycarbene complexes 1 is reported. This method involves the alkylation of acylate complexes 7 with alkyldiphenylsulfonium salts 10 with a variety of functionalized alkyl groups. The alkylation of tetramethylammonium pentacarbonyl-(1-oxyalkylidene)chromate(0) 7a-c, tetramethylammonium pentacarbonyl(1-oxymethylidene)molybdate(0) 7d, and pentacarbonyl(1-oxymethylidene)tungstate(0) 7e with alkyldiphenylsulfonium salts 10 proceeded smoothly under mild conditions to give the corresponding alkoxycarbene complexes 12-39 in good to high yields. Competitive alkylation of 7a with methyl-11 and isopropyldiphenylsulfonium tetrafluoroborate 40 shows a higher reactivity of the isopropyl group, suggesting the participation of an S-O sulfurane intermediate 41.

Alkyl diaryl sulfonium salts

Alkyl diaryl sulfonium salts, e.g., cyclopropyl diphenylsulfonium tetrafluoroborate, are useful as hypoglycemic agents.