334709-81-8

Basic information

• Product Name: 4-(4-chlorophenyl)-1,2,5-thiadiazole-3-carboxamide
• Synonyms: 4-(4-chlorophenyl)-1,2,5-thiadiazole-3-carboxamide
• CAS NO: 334709-81-8
• Molecular Weight: 239.685
• Mol File: 334709-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-1,2,5-thiadiazole-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-1,2,5-thiadiazole-3-carboxamide(334709-81-8)
• EPA Substance Registry System: 4-(4-chlorophenyl)-1,2,5-thiadiazole-3-carboxamide(334709-81-8)

Safety Data

• Hazardous Substances Data: 334709-81-8(Hazardous Substances Data)

Upstream product

• 71426-50-1 Syn-α-Brom-p-chlor-acetophenon oxim 
• 33866-48-7 3-(4-chloro-phenyl)-isoxazol-5-ylamine 

Relevant articles and documents

A modified procedure for the synthesis of 5-amino-3-arylisoxazoles and their reactions with tetrasulfur tetranitride antimony(V) chloride complex (S4N4·SbCl5): Novel synthesis of 3-aryl-1,2,5-thiadiazole-4-carboxamides

Dropwise addition of α-bromo ketoximes to a solution of KCN in MeOH at room temperature gave 5-amino-3-arylisoxazoles in moderate to good yields. Treatment of the isoxazoles prepared with tetrasulfur tetranitride antimony (V) chloride complex (S4N4·SbCl5) in toluene at 100°C afforded novel 3-aryl-1,2,5-thiadiazole-4-carboxamides.