334757-22-1

Upstream product

• 146176-60-5 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carbonyl chloride 
• 62258-06-4 thioacetic acid S-((S)-1-phenylethyl) ester 
• 33877-11-1 (S)-1-mercapto-1-phenylethane 
• 79-30-1 isobutyryl chloride 
• 334757-17-4 (-)-(S)-S-Phenylethyl 2,2,4,4-tetramethyl-1,3-oxazolidine-3-thiocarboxylate 

Downstream Products

• 334757-39-0 (-)-(R)-S-2-[N-(2-Hydroxy-1,1-dimethylethyl)-aminocarbonylthio]-4-methyl-2-phenyl-3-pentanone 

Relevant academic research and scientific papers

The configurational stability of an enantioenriched α-thiobenzyllithium derivative and the stereochemical course of its electrophilic substitution reactions; synthesis of enantiomerically pure, tertiary benzylic thiols

The lithium compound (S)-7, formed by deprotonation of the (S)-S-1-phenylethyl thiocarbamate (S)-10, is configurationally stable at -70°C. Even at elevated temperatures it racemizes only very slowly. It represents the first essentially enantiopure αthioca