33477-43-9

Basic information

• Product Name: Glycinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-
• CAS NO: 33477-43-9
• Molecular Formula: C15H21N3O4
• Molecular Weight: 307.349
• Mol File: 33477-43-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Glycinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Glycinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-(33477-43-9)
• EPA Substance Registry System: Glycinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-(33477-43-9)

Safety Data

• Hazardous Substances Data: 33477-43-9(Hazardous Substances Data)

Upstream product

• 3496-11-5 2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate 
• 598-41-4 H-Gly-NH₂ 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 1668-10-6 glycinamide hydrochloride 

Downstream Products

• 1025831-19-9 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid benzyl ester 
• 1025941-24-5 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid tert-butyl ester 
• 147424-44-0 Boc-Asp(OBzl)-Val-Val-Gly-NH₂ 
• 147424-43-9 Z-Asp(OtBu)-Val-Val-Gly-NH₂ 
• 147424-50-8 Z-Val-Asp(OtBu)-Val-Gly-NH₂ 
• 147424-40-6 Z-Asp(OtBu)-Val-Gly-NH₂ 
• 165901-00-8 H-Asp(OBzl)-Val-Val-Gly-NH₂ 
• 147424-36-0 Z-Val-Val-Gly-NH₂ 
• 122752-15-2 deltorphin C 
• 132125-58-7 H-Tyr-D-Ala-Phe-Val-Asp-Val-Gly-NH₂ 
• 98035-61-1 H-Val-Gly-NH₂ 

Relevant articles and documents

Enzymatic C-terminal amidation of amino acids and peptides

Herein, we describe two versatile and high yielding enzymatic approaches for the conversion of semi-protected amino acid and peptidyl C-terminal α-carboxylic acids into their corresponding amides. In the first approach, the lipase Candida antarctica lipase-B (Cal-B), and in the second approach, the protease Subtilisin A, are used, respectively. We found that by using the ammonium salt of the α-carboxylic acid instead of separate ammonia sources, the enzymatic amidation reactions proceeded much faster without side reactions and gave near to quantitative yields of products.

Unique sequence in deltorphin C confers structural requirement for δ opioid receptor selectivity

A series of deltorphin C (H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2) analogues were synthesized to assess the consequences of changing anionic and hydrophobic residues on δ receptor selectivity.Analogues with altered C-terminal groups, inverted sequences, or es