33477-43-9

Upstream product

• 3496-11-5 2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate 
• 598-41-4 H-Gly-NH₂ 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 1668-10-6 glycinamide hydrochloride 

Downstream Products

• 1025831-19-9 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid benzyl ester 
• 1025941-24-5 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid tert-butyl ester 
• 147424-44-0 Boc-Asp(OBzl)-Val-Val-Gly-NH₂ 
• 147424-43-9 Z-Asp(OtBu)-Val-Val-Gly-NH₂ 
• 147424-50-8 Z-Val-Asp(OtBu)-Val-Gly-NH₂ 
• 147424-40-6 Z-Asp(OtBu)-Val-Gly-NH₂ 
• 165901-00-8 H-Asp(OBzl)-Val-Val-Gly-NH₂ 
• 147424-36-0 Z-Val-Val-Gly-NH₂ 
• 122752-15-2 deltorphin C 
• 132125-58-7 H-Tyr-D-Ala-Phe-Val-Asp-Val-Gly-NH₂ 
• 98035-61-1 H-Val-Gly-NH₂ 

Relevant academic research and scientific papers

Enzymatic C-terminal amidation of amino acids and peptides

Herein, we describe two versatile and high yielding enzymatic approaches for the conversion of semi-protected amino acid and peptidyl C-terminal α-carboxylic acids into their corresponding amides. In the first approach, the lipase Candida antarctica lipase-B (Cal-B), and in the second approach, the protease Subtilisin A, are used, respectively. We found that by using the ammonium salt of the α-carboxylic acid instead of separate ammonia sources, the enzymatic amidation reactions proceeded much faster without side reactions and gave near to quantitative yields of products.

Synthesis and biological evaluation of analogues of the antibiotic pantocin B

Strains of the bacteria Erwinia herbicola produce antibiotics that effectively control E. amylovora, the bacterial pathogen responsible for the plant disease fire blight. Pantocin B was the first of these antibiotics to be characterized, and a flexible sy

Unique sequence in deltorphin C confers structural requirement for δ opioid receptor selectivity

A series of deltorphin C (H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2) analogues were synthesized to assess the consequences of changing anionic and hydrophobic residues on δ receptor selectivity.Analogues with altered C-terminal groups, inverted sequences, or es