33490-49-2

Upstream product

• 420-04-2 CYANAMID 
• 93-89-0 benzoic acid ethyl ester 
• 64-17-5 ethanol 
• 100-52-7 benzaldehyde 
• 5333-86-8 ethyl benzimidate hydrochloride 

Downstream Products

• 55383-55-6 2-phenyl-benzo[4,5]imidazo[1,2-a][1,3,5]triazin-4-ylamine 
• 114565-02-5 N²-Cyan-N¹-(ethyliminomethyl-λ⁶-sulfanyliden)benzamidin 
• 111268-20-3 N¹-(Benzyliminomethyl-λ⁶-sulfanyliden)-N²-cyanbenzamidin 
• 111268-37-2 1-Ethyl-5-phenyl-1λ⁴,2,4,6-thiatriazin-3-amin 
• 111268-38-3 1-Benzyl-5-phenyl-1λ⁴,2,4,6-thiatriazin-3-amin 
• 111268-19-0 N²-Cyan-N¹-(tetrahydro-1-imino-λ⁶-thiophen-1-yliden)benzamidin 
• 107325-99-5 5-Methyl-2,7-diphenylpyrimido<5,4-b><1λ⁴,4>thiazin-4-amin-5-oxid 
• 99967-80-3 4-Amino-2-phenyl-5-thiazolcarbonsaeure-methylester 
• 114565-06-9 N²-Cyan-N¹-6-sulfanyliden>benzamidin 
• 114565-08-1 N²-Cyan-N¹-6-sulfanyliden>benzamidin 
• 114565-20-7 1,6-Dimethyl-1-(methylsulfonylimino)-3-phenyl-1λ⁶,2,4-thiadiazin-5-amin 
• 114565-09-2 N¹-<(Benzoylimino)ethylmethyl-λ⁶-sulfanyliden>-N²-cyanbenzamidin 
• 114565-29-6 N-<1,6-Dimethyl-1-(methylsulfonylimino)-3-phenyl-1λ⁶,2,4-thiadiazin-5-yl>-N'-phenylharnstoff 
• 111268-36-1 1-Methyl-5-phenyl-1λ⁴,2,4,6-thiatriazin-3-amin 

Relevant academic research and scientific papers

Highly efficient cyanoimidation of aldehydes

"Chemical Equation Presented" Cyanoimidation of aldehydes using cyanamide as a nitrogen source and using NBS as an oxidant was achieved in high yields without the addition of a catalyst. The method has several advantages, Including mild conditions, simple workflow, and inexpensive reagents. The reaction proceeds in a one-pot manner, giving rise to the formation of intermolecular C-N and C-O bonds. Subsequently, the substituted W-cyanobenimidate products may also undergo a cyclization reaction to give 1,2,4-triazole derivatives in high yields.

Easy access to triazoles, triazolopyrimidines, benzimidazoles and imidazoles from imidates

We have described a new and easy synthesis of triazoles, triazolopyrimidines, benzimidazoles and imidazoles variously substituted based on the reaction of imidates with diamine derivatives. The products were obtained in moderate to good yields. A general mechanism for the reactions is proposed.

Adenosine receptor ligands and their use in the treatment of disease

The invention relates to cyclic heteroaromatic compounds, containing at least one nitrogen atom, and to their use in the manufacture of medicaments for the treatment of diseases, related to adenosine receptor modulators, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses, hypoxia, ischaemia, seizure, substance abuse, sedation and they may be active as muscle relaxants, antipsychotics, anti epileptics, anticonvulsants and cardiaprotective agents.