334931-07-6

Basic information

• Product Name: (4-ethynylphenyl)(4-hydroxyphenyl)methanone
• Synonyms: (4-ethynylphenyl)(4-hydroxyphenyl)methanone
• CAS NO: 334931-07-6
• Molecular Weight: 222.243
• Mol File: 334931-07-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-ethynylphenyl)(4-hydroxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-ethynylphenyl)(4-hydroxyphenyl)methanone(334931-07-6)
• EPA Substance Registry System: (4-ethynylphenyl)(4-hydroxyphenyl)methanone(334931-07-6)

Safety Data

• Hazardous Substances Data: 334931-07-6(Hazardous Substances Data)

Upstream product

• 935-14-8 1,4-diethynylbenzene 
• 108-95-2 phenol 
• 100-66-3 methoxybenzene 
• 334931-05-4 acetic acid 4-[4-(3-hydroxy-3-methyl-but-1-ynyl)-benzoyl]-phenyl ester 

Downstream Products

• 334931-06-5 trifluoro-methanesulfonic acid 4-(4-ethynyl-benzoyl)-phenyl ester 

Relevant articles and documents

Visible Light Copper Photoredox-Catalyzed Aerobic Oxidative Coupling of Phenols and Terminal Alkynes: Regioselective Synthesis of Functionalized Ketones via C C Triple Bond Cleavage

Direct oxidative coupling of phenols and terminal alkynes was achieved at room temperature by a visible-light-mediated copper-catalyzed photoredox process. This method allows regioselective synthesis of hydroxyl-functionalized aryl and alkyl ketones from simple phenols and phenylacetylene via C C triple bond cleavage. 47 examples were presented. From a synthetic perspective, this protocol offers an efficient synthetic route for the preparation of pharmaceutical drugs, such as pitofenone and fenofibrate.