33497-37-9Relevant academic research and scientific papers
Copper-catalyzed [2+3]-annulation of N-H imines with vinyl azides: Access to polyaryl 2: H -imidazoles
Zhu, Zhongzhi,Lin, Hanze,Liang, Baihui,Huang, Junjie,Liang, Wanyi,Chen, Lu,Huang, Yubing,Chen, Xiuwen,Li, Yibiao
supporting information, p. 5621 - 5624 (2020/06/19)
A practical method for the synthesis of 2H-imidazoles via a [2+3] annulation of N-H imines with vinyl azides using a copper catalyst is developed. In this conversion, environmentally friendly oxygen is used as the sole oxidant and N2 and H2O are the only by-products. The catalytic transformation, operating under mild conditions, is operationally simple and is considered as a readily available catalytic system having good substrate and functional compatibility with high atom-efficiency without the need for additional ligands or additives.
Hydrogen bond directed aerobic oxidation of amines via photoredox catalysis
Wang, Hongyu,Man, Yunquan,Wang, Kaiye,Wan, Xiuyan,Tong, Lili,Li, Na,Tang, Bo
supporting information, p. 10989 - 10992 (2018/10/08)
An application of H-bonding interactions for directing the α-C-H oxidation of amines to amides and amino-ketones catalyzed by an organic photocatalyst is reported. The high efficiency of this method is demonstrated by the aerobic oxidation of pyrrolidines, diarylamines and benzylamines bearing urea groups with high yields and a wide substrate scope.
Introducing Glycerol as a Sustainable Solvent to Organolithium Chemistry: Ultrafast Chemoselective Addition of Aryllithium Reagents to Nitriles under Air and at Ambient Temperature
Rodríguez-álvarez, María J.,García-álvarez, Joaquín,Uzelac, Marina,Fairley, Michael,O'Hara, Charles T.,Hevia, Eva
, p. 1720 - 1725 (2018/01/27)
Edging closer towards developing air and moisture compatible polar organometallic chemistry, the chemoselective and ultrafast addition of a range of aryllithium reagents to nitriles has been accomplished by using glycerol as a solvent, at ambient temperature in the presence of air, establishing a novel sustainable access to aromatic ketones. Addition reactions occur heterogeneously (“on glycerol conditions”), where the lack of solubility of the nitriles in glycerol and the ability of the latter to form strong intermolecular hydrogen bonds seem key to favouring nucleophilic addition over competitive hydrolysis. Remarkably, PhLi exhibits a greater resistance to hydrolysis working “on glycerol” conditions than “on water”. Introducing glycerol as a new solvent in organolithium chemistry unlocks a myriad of opportunities for developing more sustainable, air and moisture tolerant main-group-metal-mediated organic synthesis.
Synthesis of aryl ketones via decarboxylation of aromatic acids under solvothermal condition
Rai, K.M. Lokanatha,Babu, M. Suresh,Byrappa
experimental part, p. 1395 - 1396 (2012/08/27)
Aryl ketones were prepared by the condensation of aromatic carboxylic acids with alkyl/aryl nitrile via the decarboxylation of carboxylic acids under solvothermal condition. All the compounds were characterized by comparing with standard samples prepared by the known literature method.
On alkylideneamidosulfenyl chlorides and 1-thia-2-azoniaallene salts
Wirschun, Wolfgang G.,Hitzler, Martin G.,Jochims, Johannes C.,Groth, Ulrich
, p. 2627 - 2635 (2007/10/03)
X-Ray-diffraction analysis of 1Bu2C=N-SCl (4b) revealed an almost linear C=N=S unit with an S=N bond order of ca. 1.9 (Fig. 1), in agreement with the structure of a 1-thia-2-azoniaallene chloride. With SCl2 and SbCl5
