33523-70-5Relevant academic research and scientific papers
Regioselective Mg-promoted C-acylation of stilbene and acenaphthylene derivatives
Nishiguchi, Ikuzo,Yamamoto, Yoshimasa,Sakai, Masahiro,Ohno, Toshinobu,Ishino, Yoshio,Maekawa, Hirofumi
, p. 759 - 762 (2007/10/03)
Treatment of stilbene and acenaphthylene derivatives with Mg turnings in the presence of aliphatic acid anhydrides and trimethylsilyl chloride (TMSCl) in N,N-dimethylformamide (DMF) brought about a facile and efficient cross-coupling to give C-acylation p
Solid-Liquid Phase-Transfer Catalysis without Solvent: Selective Mono- and Di-alkylation of Benzyl Methyl Ketone
Aranda, Alfonso,Diaz, Angel,Diez-Barra, Enrique,Hoz, Antonio de la,Moreno, Andres,Sanchez-Verdu, Prado
, p. 2427 - 2430 (2007/10/02)
The alkylation of benzyl methyl ketone 1 has been performed by phase-transfer catalysis without solvent.Excellent yields of mono- 2 and di-alkyl derivatives 3 and 4 were obtained through general, selective and mild conditions.
Rearrangement of Ketones. Part 4. Aluminium Chloride Catalysed Rearrangement of Some 2,2-Dialkyl-1-phenyl-1-propan-1-ones
Fernandez-Monreal, Maria C.,Ruiz, Maria P.
, p. 440 - 472 (2007/10/02)
Four α,α,α-trisubstituted acetophenones ((1):R1=R2=R3=CH3; (2):R1=R2=CH3, R3=CH2CH3; (3):R1=R2=CH3, R3=CH2Ph; (4):R1=CH3, R2=CH2CH3, R3=CH2Ph) were prepared.Ketones (1)-(4) were treated with aluminium chloride to induce rearrangement to alkyl ketones.The phenyl ketones behaved as follows: (1) gave 3-methyl-3-phenylbutan-2-one (7), (2) gave 3-methyl-3-phenylpentan-2-one (8) and 2-methyl-2-phenylpentan-3-one (9), (3) gave 3-methyl-3,4-diphenylbutan-2-one (10) and 3-methyl-1,3-diphenylbutan-2-one (11), and (4) gave 3-methyl-1,3-diphenylpentan-2-one (12), 2-methyl-1,2-diphenylpentan-3-one (13) and 3-benzyl-3-phenylpentan-2-one (14).A tentative mechanism for the rearrangement is proposed.
