335254-69-8

Usage

Uses

Used in Organic Synthesis:
Tert-butyl (4-iodo-2-nitrophenyl)carbamate is used as a building block for the preparation of various pharmaceuticals and agrochemicals. Its unique structure and reactivity contribute to the development of new and effective compounds in these industries.
Used in Chemical Research:
Tert-butyl (4-iodo-2-nitrophenyl)carbamate is employed as a reagent in the synthesis of biologically active compounds. Its versatility allows researchers to explore its potential in creating novel molecules with desired properties.
Used in Materials Science:
Tert-butyl (4-iodo-2-nitrophenyl)carbamate may have potential applications in materials science, where its unique chemical properties could be utilized to develop new materials with specific characteristics.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 20691-72-9 4-iodo-2-nitroaniline 
• 88-74-4 2-nitro-aniline 
• 75-65-0 tert-butyl alcohol 
• 503-38-8 trichloromethyl chloroformate 

Downstream Products

• 335255-04-4 (2-nitro-4-pyridin-3-yl-phenyl)-carbamic acid tert.-butyl ester 
• 335254-78-9 (4-Furan-3-yl-2-nitro-phenyl)-carbamic Acid tert.-Butyl Ester 
• 335255-13-5 (2-nitro-4-trimethylsilanylethynyl-phenyl)-carbamic acid tert.-butyl ester 
• 335254-91-6 (4-benzofuran-2-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester 
• 335254-74-5 (2-nitro-4-thiophen-3-yl-phenyl)-carbamic acid tert.-butyl ester 
• 335254-79-0 (4-naphthalen-1-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester 
• 335255-12-4 [4-(6-Benzyloxy-pyridin-3-yl)-2-nitro-phenyl]-carbamic Acid tert.-Butyl Ester 
• 335255-08-8 (4-benzoyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester 
• 335255-09-9 (2-nitro-4-tributylstannanyl-phenyl)-carbamic acid tert.-butyl ester 
• 1453393-66-2 4-[3’-(1''H-imidazol-1''-yl)phenyl]-8-(3'''-iodophenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one 
• 1453393-68-4 4-[3’-(1''H-imidazol-1''-yl)phenyl]-8-(4'''-iodophenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one 
• 1453393-54-8 4-[3’-(1''H-imidazol-1''-yl)phenyl]-8-iodo-2,3-dihydro-1H-1,5-benzodiazepin-2-one 
• 1453393-56-0 8-(3'''-bromophenyl)-4-[3’-(1''H-imidazol-1''-yl)phenyl]-2,3-dihydro-1H-1,5-benzodiazepin-2-one 
• 1453393-58-2 8-(4'''-bromophenyl)-4-[3’-(1''H-imidazol-1''-yl)phenyl]-2,3-dihydro-1H-1,5-benzodiazepin-2-one 

Relevant academic research and scientific papers

New class of bioluminogenic probe based on bioluminescent enzyme-induced electron transfer: BioLeT

Bioluminescence imaging (BLI) has advantages for investigating biological phenomena in deep tissues of living animals, but few design strategies are available for functional bioluminescent substrates. We propose a new design strategy (designated as bioluminescent enzyme-induced electron transfer: BioLeT) for luciferin-based bioluminescence probes. Luminescence measurements of a series of aminoluciferin derivatives confirmed that bioluminescence can be controlled by means of BioLeT. Based on this concept, we developed bioluminescence probes for nitric oxide that enabled quantitative and sensitive detection even in vivo. Our design strategy should be applicable to develop a wide range of practically useful bioluminogenic probes.

Synthesis and biological evaluation of novel 2,3-dihydro-1H-1,5- benzodiazepin-2-ones; Potential imaging agents of the metabotropic glutamate 2 receptor

A focused library of novel 2,3-dihydro-1H-1,5-benzodiazepin-2-ones containing sites for 11C-, 18F- and 123I- labelling have been prepared and evaluated against membrane expressing human recombinant metabotropic glutamate 2 receptor (mGluR2). The compounds were found to be non-competitive antagonists with nanomolar affinity. HPLC evaluation of the physiochemical properties of these compounds identified two candidates for PET and SPECT imaging of mGluR2.

NOVEL BENZODIAZEPINONES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR FUNCTIONS AND NEUROLOGICAL USES THEREOF

The present invention relates to novel benzodiazepinone compounds of Formulae (I) wherein R1, R2, R4, R6, R7, R8, R9, and R10 are as defined herein. The invention also

Glutamate receptor antagonists

The present invention is a compound of formula wherein X is an ethynediyl group, R1, R2and R3are as defined in the specification.

Glutamate receptor antagonists

The present invention relates to compounds of with a base structure of formula 1 The compounds of formula I are shown to have activity as metabotropic glutamate receptor antagonists.