3353-51-3Relevant articles and documents
Electrooxidative Dearomatization to Spiroisoxazolines: Application to Total Synthesis of Xanthoisoxazoline B
Chen, Dengfeng,He, Tianyu,Jin, Yongcan,Huang, Shenlin
supporting information, p. 286 - 290 (2021/11/13)
The synthesis of spiroisoxazoline molecules has been developed via anodic oxidative dearomatization of 4-methoxybenzyl oximes. The reaction is thought to proceed through 5-exo C?O bond-forming cyclization of oxime radicals with arenes on the basis of cycl
Oxygen surface groups of activated carbon steer the chemoselective hydrogenation of substituted nitroarenes over nickel nanoparticles
Ren, Yujing,Wei, Haisheng,Yin, Guangzhao,Zhang, Leilei,Wang, Aiqin,Zhang, Tao
supporting information, p. 1969 - 1972 (2017/02/15)
Oxygen surface groups of activated carbon, produced by nitric acid treatment, are not only able to prevent Ni particles from sintering but are also able to preferentially interact with the nitro group of substituted nitroarenes. The resulting Ni/ACOX catalyst is highly active and chemoselective for hydrogenation of nitroarenes to produce functionalized anilines and oximes.
Synthesis of Nitriles from Aldoximes and Primary Amides Using XtalFluor-E
Keita, Massaba,Vandamme, Mathilde,Paquin, Jean-Fran?ois
, p. 3758 - 3766 (2015/11/28)
The dehydration reaction of aldoximes and amides for the synthesis of nitriles using [Et2NSF2]BF4 (XtalFluor-E) is described. Overall, the reaction proceeds rapidly (normally 1 h) at room temperature in an environmentally benign solvent (EtOAc) with only a slight excess of the dehydrating agent (1.1 equiv). A broad scope of nitriles can be prepared, including chiral nonracemic ones. In addition, in a number of cases, further purification of the nitrile after the workup was not required.