33545-44-7

Usage

Uses

Used in Pharmaceutical Research:
Ethyl 3-(2-furyl)pyrazole-5-carboxylate, 98% is used as a building block for the synthesis of biologically active compounds and pharmaceutical products. Its versatile reactivity and functional groups contribute to the development of new medications and therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, Ethyl 3-(2-furyl)pyrazole-5-carboxylate, 98% serves as an essential component in creating complex organic molecules. Its high purity ensures that the reactions are more controlled and precise, leading to the production of desired compounds with fewer impurities.
Used in Research and Development:
Due to its high purity, Ethyl 3-(2-furyl)pyrazole-5-carboxylate, 98% is ideal for research and development applications. It allows scientists to have better control over chemical compositions, which is crucial for advancing the understanding of chemical reactions and the creation of new chemical entities.

InChI:InChI=1/C10H10N2O3/c1-2-10(13)15-9-6-7(11-12-9)8-4-3-5-14-8/h3-6H,2H2,1H3,(H,11,12)

Upstream product

• 64-17-5 ethanol 
• 871239-83-7 3-furan-2-yl-5-trichloromethyl-1H-pyrazole 
• 36983-35-4 ethyl 4-(furan-2-yl)-2,4-dioxobutyrate 
• 1381932-41-7 C₁₂H₁₃NO₇ 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 33008-49-0 4-furan-2-yl-4-oxo-but-2-ynoic acid ethyl ester 

Downstream Products

• 84978-67-6 3(5)-hydroxymethyl-5(3)-(2-furyl)pyrazole 

Relevant academic research and scientific papers

An approach to 2,4-substituted pyrazolo[1,5-a]pyridines and pyrazolo[1,5-a]azepines by ring-closing metathesis

The ring-closing metathesis (RCM) reactions of dienylpyrazoles have been employed in the synthesis of pyrazolo[1,5-a]pyridine and pyrazolo[1,5-a]azepine derivatives. Based on this approach, the diastereoselective synthesis of potential peptidomimetics containing four amino acid residues with the second (i+1) and third (i+2) fragments having been substituted by bicyclic frameworks is described. The N-allylation of readily available 3,5-substituted pyrazoles followed by ring-closing metathesis of the resulting 1,5-diolefinic derivatives leads to the formation of 2,4-substituted pyrazolo[1,5-a]pyridines and pyrazolo[1,5-a]azepines in high yields. The application of this protocol to the diastereoselective synthesis of potential peptidomimetics is described. Copyright

Cascade regioselective synthesis of pyrazoles from nitroallylic acetates and N-tosyl hydrazine

A simple, practical, and regioselective synthetic protocol for the formation of pyrazoles was developed. Unlike all other previously reported reactions of nitroallylic acetates, this process was initiated by a S N2 reaction at the electrophilic γ site. A plausible mechanism for the cascade SN2-Michael synthesis is proposed.

Haloacetylated enol ethers, 19: Synthesis of 3-(2-thienyl)- and 3-(2-furyl)-5-trihalomethyl substituted azoles

Heterocyclization of 1,1,1-trifluoro[chloro]-4-methoxy-4-[2-tienyl]-3- buten-2-one and 1,1,1-trifluoro[chloro]-4-methoxy-4-[2-furyl]-3-buten-2-ones into isoxazoles and pyrazoles derivatives as a new type of trihalomethylated bicyclic heterocycles is reported. Georg Thieme Verlag Stuttgart.