33554-28-8

Upstream product

• 124-68-5 2-Amino-2-methyl-1-propanol 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 33554-30-2 2-(4-chlorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 

Relevant academic research and scientific papers

Palladium-catalyzed electrophilic C–H fluorination of arenes using oxazoline as a removable directing group

Dimethyloxazoline was rationally designed to act as a removable ortho-directing group (DG) for the palladium-catalyzed C–H electrophilic fluorination of arenes. Using NFSI as the fluorinating agent, and Pd(II), Ag(I) catalytic system, electrophilic C(sp2–H) ortho-fluorination took place on a variety of aryl substrates to afford the corresponding mono- and di-fluorinated products.

NEW COMPOUNDS I/418

There is provided compounds of formula I, wherein R1 to R7 have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.