33561-65-8Relevant academic research and scientific papers
REACTIONS OF DICHLOROMETHANE WITH THIOANIONS. 2. FORMATION OF 5-ALKYL-1,3,5-DITHIAZINANES, 3,5-DIALKYL-1,3,5-THIADIAZINANES, AND 1,3,5-TRIALKYL-1,3,5-TRIAZINANES BY REACTION OF DICHLOROMETHANE WITH SODIUM SULFIDE AND MONOALKYLAMINES
Torres, Martin,Vega, Juan C.
, p. 125 - 130 (2007/10/03)
The reaction of dichloromethane with sodium sulfide and monoalkylamines, catalyzed by polyethyleneglycol 1,500, is studied.A mixture of 5-alkyl-1,3,5-dithiazinane, 3,5-dialkyl-1,3,5-thiadiazinane, and 1,3,5-trialkyl-1,3,5-triazinane is obtained.The proportion of these heterocycles depends on the amine structure and the presence of sodium hydroxide. - Key words: 5-Alkyl-1,3,5-dithiazinanes; 3,5-dialkyl-1,3,5-thiadiazinanes; dichloromethane double substitution; polyethyleneglycol as catalyst
Dichloromethane as a Reactant in the Synthesis of 1,2,3,4-Tetrahydropyrimidine Derivatives
Martens, Thierry,Souquet, Florence
, p. 1671 - 1683 (2007/10/02)
5-p-methoxyphenyl-1,2-dithiole-3-thione (Sulfarlem) reacts with primary amines in dichloromethane to give in good yield 1,3-dialkyl-6-methoxyphenyl-1,2,3,4-tetrahydropyrimidine-5-carbothioamides.In this reaction dichloromethane serves as a C-1 unit donor yielding, in the presence of elemental sulphur, 1,3,5-trisubstituted 1,3,5-triazanes and 3,5-disubstituted 1,3,5-thiadiazanes.These Mannich-type compounds react with enamine intermediates to give the title products.
