33566-57-3Relevant articles and documents
An expeditious entry to rare tetrahydroimidazo[1,5-c]pyrrolo[1,2-a]pyrimidin-7(8H)-ones: A single-step gateway synthesis of glochidine congeners
Seo, Jeong Moo,Hassan, Ahmed H.E.,Lee, Yong Sup
supporting information, (2019/11/26)
A single-step gateway synthesis of glochidine and its congeners that possess the rare uncommon tetrahydroimidazo[1,5-c]pyrrolo[1,2-a]pyrimidine core was developed employing histamine and readily available γ-ketoesters. Key features of the developed reaction involve tandem three C–N bonds formation and concomitant annulation of two rings in one pot to access this unique and complex tricyclic structure. Exploration of the unknown bioactivity of these compounds revealed that they elicit antiproliferative activity comparable to the anticancer drug imatinib against 6 cancer cell lines.
Gold and platinum catalyzed cascade reaction of propargyl acetates bearing terminal alkynes or methyl ketones
Kusakabe, Taichi,Kato, Keisuke
experimental part, p. 1511 - 1517 (2011/03/22)
A gold (III)-catalyzed cascade reaction of propargyl acetates bearing an extra terminal alkyne (1) afforded γ-keto esters 3 and lactones 4. These products should be generated through allenyl ketone intermediate B via a 1,2-acyloxy cyclization/fragmentatio
Synthesis of 13-oxo-(Z)-9-octadecenoic acid and 15-oxo-(Z)-11-icosenoic acid, arrestants of Oryzaephilus surinamensis L.
Nakajima,Okamura,Takeda,Sugawa,Tateishi,Iwasa,Baba
, p. 551 - 552 (2007/10/03)
Two arrestants of the sawtoothed grain beetle (Oryzaephilus surinamensis L.), 13-oxo-(Z)-9-octadecenoic acid and 15-oxo-(Z)-11-icosenoic acid, were synthesized for the first time by utilizing a Z-selective Wittig reaction.
