33568-61-5Relevant academic research and scientific papers
Formal total synthesis of camptothecin via ring-closing metathesis strategy
Chavan, Subhash P.,Pasupathy,Venkatraman,Kale, Ramesh R.
, p. 6879 - 6882 (2007/10/03)
A formal total synthesis of camptothecin 1 is presented. The key steps include construction of the D-ring of camptothecin featuring an efficient ring-closing metathesis (RCM) reaction and the subsequent Michael addition of nitropropane across the double b
